Name | Number of supported studies | Average coverage | |
---|---|---|---|
microglial cell | 7 studies | 23% ± 8% | |
macrophage | 6 studies | 21% ± 4% | |
retinal rod cell | 5 studies | 23% ± 6% | |
endothelial cell | 4 studies | 19% ± 4% | |
retinal bipolar neuron | 4 studies | 22% ± 4% | |
glutamatergic neuron | 4 studies | 42% ± 15% | |
oligodendrocyte | 4 studies | 21% ± 4% | |
classical monocyte | 3 studies | 20% ± 1% | |
non-classical monocyte | 3 studies | 20% ± 3% | |
epithelial cell | 3 studies | 24% ± 8% | |
rod bipolar cell | 3 studies | 27% ± 3% | |
GABAergic neuron | 3 studies | 41% ± 9% | |
astrocyte | 3 studies | 24% ± 5% | |
oligodendrocyte precursor cell | 3 studies | 22% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 1448.29 | 21 / 21 | 100% | 9.51 | 504 / 504 |
esophagus | 100% | 1442.32 | 1445 / 1445 | 100% | 11.67 | 183 / 183 |
prostate | 100% | 1316.64 | 245 / 245 | 100% | 8.70 | 502 / 502 |
skin | 100% | 2601.36 | 1809 / 1809 | 100% | 11.51 | 472 / 472 |
thymus | 100% | 1838.45 | 653 / 653 | 100% | 12.63 | 605 / 605 |
uterus | 100% | 1247.36 | 170 / 170 | 100% | 8.84 | 459 / 459 |
lung | 100% | 1294.94 | 578 / 578 | 100% | 8.59 | 1154 / 1155 |
breast | 100% | 1189.99 | 459 / 459 | 100% | 11.61 | 1117 / 1118 |
intestine | 100% | 1312.31 | 966 / 966 | 100% | 10.09 | 526 / 527 |
stomach | 100% | 942.17 | 358 / 359 | 100% | 10.11 | 286 / 286 |
ovary | 100% | 906.58 | 180 / 180 | 100% | 7.02 | 428 / 430 |
brain | 98% | 1278.72 | 2602 / 2642 | 100% | 10.78 | 705 / 705 |
adrenal gland | 100% | 1416.94 | 258 / 258 | 98% | 7.43 | 226 / 230 |
kidney | 100% | 1031.81 | 89 / 89 | 98% | 7.01 | 885 / 901 |
pancreas | 97% | 593.11 | 319 / 328 | 99% | 8.58 | 176 / 178 |
liver | 93% | 470.92 | 210 / 226 | 75% | 2.87 | 306 / 406 |
adipose | 100% | 1260.04 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1334.04 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 13.87 | 29 / 29 |
muscle | 100% | 1166.72 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2108.57 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 8.89 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.56 | 1 / 1 |
heart | 98% | 1027.67 | 848 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 97% | 1480.97 | 897 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 4.40 | 72 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_1901992 | Biological process | positive regulation of mitotic cell cycle phase transition |
GO_0051301 | Biological process | cell division |
GO_0016567 | Biological process | protein ubiquitination |
GO_0005515 | Molecular function | protein binding |
Gene name | KLHL18 |
Protein name | Kelch like family member 18 Kelch-like protein 18 Kelch-like 18 KLHL18 protein |
Synonyms | KIAA0795 OK/SW-cl.74 |
Description | FUNCTION: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis . The BCR(KLHL18) E3 ubiquitin ligase complex mediates the ubiquitination of AURKA leading to its activation at the centrosome which is required for initiating mitotic entry . Regulates light-and dark-dependent alpha-transducin localization changes in rod photoreceptors through UNC119 ubiquitination and degradation (By similarity). Preferentially ubiquitinates the unphosphorylated form of UNC119 over the phosphorylated form (By similarity). In the presence of UNC119, under dark-adapted conditions alpha-transducin mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light (By similarity). . |
Accessions | ENST00000437353.5 F8WCL4 F8WF78 Q96B51 Q6PJF0 ENST00000433449.5 Q647K1 O94889 ENST00000232766.6 [O94889-1] ENST00000442272.1 C9J4G4 |