KIF4A report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KIF4A at tissue level.

III. Associated gene sets

GO_0007052Biological processmitotic spindle organization
GO_0008089Biological processanterograde axonal transport
GO_0000281Biological processmitotic cytokinesis
GO_0006996Biological processorganelle organization
GO_0051231Biological processspindle elongation
GO_0051256Biological processmitotic spindle midzone assembly
GO_0005876Cellular componentspindle microtubule
GO_0030496Cellular componentmidbody
GO_0016020Cellular componentmembrane
GO_0005654Cellular componentnucleoplasm
GO_0016363Cellular componentnuclear matrix
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005694Cellular componentchromosome
GO_0005875Cellular componentmicrotubule associated complex
GO_1904115Cellular componentaxon cytoplasm
GO_0003677Molecular functionDNA binding
GO_0051536Molecular functioniron-sulfur cluster binding
GO_0003777Molecular functionmicrotubule motor activity
GO_0008017Molecular functionmicrotubule binding
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKIF4A
Protein nameChromosome-associated kinesin KIF4A (Chromokinesin-A)
Kinesin-like protein
SynonymsKIF4
DescriptionFUNCTION: Iron-sulfur (Fe-S) cluster binding motor protein that has a role in chromosome segregation during mitosis . Translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis . May play a role in mitotic chromosomal positioning and bipolar spindle stabilization (By similarity). .

AccessionsQ6PKB2
ENST00000374403.4 [O95239-1]
O95239