KIF23 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KIF23 at tissue level.

III. Associated gene sets

GO_0000022Biological processmitotic spindle elongation
GO_0000281Biological processmitotic cytokinesis
GO_0051256Biological processmitotic spindle midzone assembly
GO_0007018Biological processmicrotubule-based movement
GO_0032467Biological processpositive regulation of cytokinesis
GO_0030496Cellular componentmidbody
GO_0005874Cellular componentmicrotubule
GO_0072686Cellular componentmitotic spindle
GO_0005813Cellular componentcentrosome
GO_0005654Cellular componentnucleoplasm
GO_0005871Cellular componentkinesin complex
GO_0005925Cellular componentfocal adhesion
GO_0090543Cellular componentFlemming body
GO_0097149Cellular componentcentralspindlin complex
GO_0005829Cellular componentcytosol
GO_0005819Cellular componentspindle
GO_0005634Cellular componentnucleus
GO_0003777Molecular functionmicrotubule motor activity
GO_0008017Molecular functionmicrotubule binding
GO_0005524Molecular functionATP binding
GO_0005515Molecular functionprotein binding
GO_0016887Molecular functionATP hydrolysis activity

IV. Literature review

[source]
Gene nameKIF23
Protein nameKinesin family member 23
Kinesin-like protein
Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)
SynonymsKNSL5
MKLP1
DescriptionFUNCTION: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. .

AccessionsH7BYN4
ENST00000559279.6
H0YMJ4
ENST00000352331.8 [Q02241-2]
ENST00000561089.5
Q02241
ENST00000679126.1
ENST00000395392.6
ENST00000647715.1 [Q02241-1]
H0YME6
ENST00000260363.9 [Q02241-1]
A0A2R8Y531
ENST00000558346.5
ENST00000643966.1
A0A2U3TZL8
A0A7I2V5Y5