KCTD8 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0051260Biological processprotein homooligomerization
GO_0008277Biological processregulation of G protein-coupled receptor signaling pathway
GO_0042995Cellular componentcell projection
GO_0043235Cellular componentreceptor complex
GO_0042734Cellular componentpresynaptic membrane
GO_0045211Cellular componentpostsynaptic membrane
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKCTD8
Protein namePotassium channel tetramerization domain containing 8
BTB/POZ domain-containing protein KCTD8
Synonyms
DescriptionFUNCTION: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity). .

AccessionsENST00000360029.4
ENST00000515268.1
H0Y9S2
Q6ZWB6