Name | Number of supported studies | Average coverage | |
---|---|---|---|
oligodendrocyte | 15 studies | 44% ± 17% | |
glutamatergic neuron | 11 studies | 36% ± 21% | |
endothelial cell | 9 studies | 22% ± 6% | |
GABAergic neuron | 7 studies | 25% ± 10% | |
neuron | 5 studies | 26% ± 9% | |
interneuron | 5 studies | 19% ± 3% | |
microglial cell | 4 studies | 19% ± 3% | |
retinal bipolar neuron | 3 studies | 17% ± 2% | |
glial cell | 3 studies | 34% ± 15% | |
rod bipolar cell | 3 studies | 30% ± 3% | |
Schwann cell | 3 studies | 65% ± 15% | |
granule cell | 3 studies | 32% ± 8% | |
oligodendrocyte precursor cell | 3 studies | 19% ± 1% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 12 studies | 37% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 4772.83 | 2642 / 2642 | 100% | 48.83 | 704 / 705 |
adrenal gland | 93% | 2012.07 | 241 / 258 | 62% | 8.40 | 143 / 230 |
lung | 94% | 1447.59 | 544 / 578 | 60% | 8.08 | 695 / 1155 |
prostate | 78% | 725.92 | 191 / 245 | 75% | 4.62 | 376 / 502 |
kidney | 82% | 684.25 | 73 / 89 | 67% | 6.72 | 605 / 901 |
thymus | 62% | 423.80 | 402 / 653 | 71% | 5.28 | 432 / 605 |
bladder | 62% | 496.24 | 13 / 21 | 57% | 6.49 | 285 / 504 |
intestine | 72% | 1268.92 | 697 / 966 | 43% | 5.12 | 225 / 527 |
ovary | 58% | 422.68 | 105 / 180 | 51% | 5.24 | 220 / 430 |
ureter | 0% | 0 | 0 / 0 | 100% | 79.99 | 1 / 1 |
esophagus | 64% | 956.85 | 925 / 1445 | 32% | 2.38 | 59 / 183 |
breast | 43% | 343.19 | 196 / 459 | 52% | 3.46 | 579 / 1118 |
uterus | 37% | 260.26 | 63 / 170 | 41% | 5.37 | 190 / 459 |
skin | 44% | 288.46 | 789 / 1809 | 35% | 5.78 | 164 / 472 |
stomach | 32% | 337.63 | 114 / 359 | 41% | 3.22 | 116 / 286 |
pancreas | 0% | 1.72 | 1 / 328 | 67% | 5.06 | 119 / 178 |
heart | 55% | 453.52 | 477 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 45% | 2.57 | 13 / 29 |
blood vessel | 39% | 300.93 | 520 / 1335 | 0% | 0 | 0 / 0 |
adipose | 34% | 247.48 | 404 / 1204 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 31% | 1.76 | 14 / 45 |
spleen | 10% | 55.09 | 25 / 241 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 10% | 0.96 | 41 / 406 |
eye | 0% | 0 | 0 / 0 | 4% | 0.26 | 3 / 80 |
muscle | 1% | 7.45 | 11 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 1.17 | 2 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006813 | Biological process | potassium ion transport |
GO_0001508 | Biological process | action potential |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0019228 | Biological process | neuronal action potential |
GO_0019229 | Biological process | regulation of vasoconstriction |
GO_0046928 | Biological process | regulation of neurotransmitter secretion |
GO_0099505 | Biological process | regulation of presynaptic membrane potential |
GO_0005513 | Biological process | detection of calcium ion |
GO_0071805 | Biological process | potassium ion transmembrane transport |
GO_0045202 | Cellular component | synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0008076 | Cellular component | voltage-gated potassium channel complex |
GO_0015269 | Molecular function | calcium-activated potassium channel activity |
GO_0015459 | Molecular function | potassium channel regulator activity |
GO_0005515 | Molecular function | protein binding |
GO_0099508 | Molecular function | voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential |
Gene name | KCNMB4 |
Protein name | Calcium-activated potassium channel subunit beta-4 (BK channel subunit beta-4) (BKbeta4) (Hbeta4) (Calcium-activated potassium channel, subfamily M subunit beta-4) (Charybdotoxin receptor subunit beta-4) (K(VCA)beta-4) (Maxi K channel subunit beta-4) (Slo-beta-4) Calcium-activated potassium channel subunit beta (BKbeta) (BK channel subunit beta) (Calcium-activated potassium channel, subfamily M subunit beta) (Charybdotoxin receptor subunit beta) (K(VCA)beta) (Maxi K channel subunit beta) (Slo-beta) |
Synonyms | |
Description | FUNCTION: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations. . FUNCTION: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. . |
Accessions | ENST00000258111.5 Q86W47 H0YC85 ENST00000531884.1 |