Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 9 studies | 40% ± 25% | |
astrocyte | 7 studies | 29% ± 11% | |
oligodendrocyte | 7 studies | 26% ± 9% | |
neuron | 5 studies | 26% ± 8% | |
endothelial cell | 5 studies | 27% ± 12% | |
GABAergic neuron | 5 studies | 38% ± 13% | |
retinal ganglion cell | 4 studies | 21% ± 5% | |
fibroblast | 4 studies | 17% ± 1% | |
ependymal cell | 3 studies | 36% ± 12% | |
endothelial cell of lymphatic vessel | 3 studies | 17% ± 1% | |
adipocyte | 3 studies | 23% ± 1% | |
interneuron | 3 studies | 39% ± 13% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 10 studies | 32% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 1627.19 | 2632 / 2642 | 100% | 13.97 | 704 / 705 |
breast | 100% | 1594.81 | 459 / 459 | 98% | 8.27 | 1099 / 1118 |
skin | 98% | 1288.68 | 1775 / 1809 | 96% | 11.01 | 455 / 472 |
thymus | 99% | 913.71 | 649 / 653 | 95% | 5.31 | 573 / 605 |
kidney | 100% | 814.78 | 89 / 89 | 93% | 9.36 | 837 / 901 |
lung | 99% | 1188.58 | 575 / 578 | 92% | 5.10 | 1059 / 1155 |
adrenal gland | 95% | 795.99 | 246 / 258 | 94% | 11.46 | 216 / 230 |
uterus | 100% | 2782.51 | 170 / 170 | 88% | 5.83 | 406 / 459 |
esophagus | 97% | 1861.94 | 1405 / 1445 | 87% | 6.62 | 160 / 183 |
prostate | 99% | 1185.98 | 242 / 245 | 83% | 3.75 | 419 / 502 |
ovary | 100% | 1226.43 | 180 / 180 | 59% | 2.22 | 254 / 430 |
bladder | 100% | 1720.48 | 21 / 21 | 58% | 3.39 | 293 / 504 |
liver | 96% | 596.80 | 216 / 226 | 56% | 2.44 | 228 / 406 |
intestine | 94% | 1963.86 | 912 / 966 | 55% | 2.50 | 290 / 527 |
stomach | 67% | 766.13 | 240 / 359 | 73% | 3.86 | 208 / 286 |
pancreas | 41% | 179.17 | 133 / 328 | 90% | 5.72 | 160 / 178 |
blood vessel | 100% | 2148.10 | 1335 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 1925.41 | 1203 / 1204 | 0% | 0 | 0 / 0 |
spleen | 99% | 751.66 | 239 / 241 | 0% | 0 | 0 / 0 |
muscle | 99% | 935.27 | 792 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 5.30 | 44 / 45 |
lymph node | 0% | 0 | 0 / 0 | 97% | 6.31 | 28 / 29 |
heart | 96% | 1748.16 | 830 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 70% | 3.08 | 56 / 80 |
peripheral blood | 25% | 274.31 | 236 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0051013 | Biological process | microtubule severing |
GO_0007283 | Biological process | spermatogenesis |
GO_0031122 | Biological process | cytoplasmic microtubule organization |
GO_0005813 | Cellular component | centrosome |
GO_0015630 | Cellular component | microtubule cytoskeleton |
GO_0008352 | Cellular component | katanin complex |
GO_0005874 | Cellular component | microtubule |
GO_0000922 | Cellular component | spindle pole |
GO_0005819 | Cellular component | spindle |
GO_0005737 | Cellular component | cytoplasm |
GO_0008017 | Molecular function | microtubule binding |
GO_0016853 | Molecular function | isomerase activity |
GO_0008568 | Molecular function | microtubule severing ATPase activity |
GO_0005515 | Molecular function | protein binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
GO_0005524 | Molecular function | ATP binding |
Gene name | KATNAL1 |
Protein name | Katanin catalytic subunit A1 like 1 Multifunctional fusion protein [Includes: Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 5.6.1.1) (p60 katanin); Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (p60 katanin-like 1)] Katanin p60 ATPase-containing subunit A-like 1 (Katanin p60 subunit A-like 1) (EC 5.6.1.1) (p60 katanin-like 1) |
Synonyms | KATNA1 |
Description | FUNCTION: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth. .; FUNCTION: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays. . FUNCTION: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity). Has microtubule-severing activity in vitro . . |
Accessions | A2A3H2 Q9BW62 ENST00000414289.5 Q5T558 ENST00000441394.1 ENST00000380617.7 B2RDY3 ENST00000380615.8 |