Insufficient scRNA-seq data for expression of IVL at single-cell level.
Insufficient scRNA-seq data for expression of IVL at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ureter | 0% | 0 | 0 / 0 | 100% | 92.23 | 1 / 1 |
esophagus | 39% | 10086.37 | 565 / 1445 | 50% | 107.68 | 92 / 183 |
tonsil | 0% | 0 | 0 / 0 | 84% | 180.10 | 38 / 45 |
bladder | 33% | 879.14 | 7 / 21 | 51% | 100.23 | 257 / 504 |
skin | 72% | 10079.05 | 1297 / 1809 | 11% | 34.00 | 54 / 472 |
uterus | 1% | 622.07 | 2 / 170 | 51% | 114.86 | 233 / 459 |
lung | 0% | 0 | 0 / 578 | 36% | 36.78 | 421 / 1155 |
thymus | 0% | 0 | 0 / 653 | 19% | 7.34 | 115 / 605 |
pancreas | 0% | 0 | 0 / 328 | 10% | 10.44 | 18 / 178 |
breast | 0% | 0 | 0 / 459 | 4% | 1.45 | 40 / 1118 |
lymph node | 0% | 0 | 0 / 0 | 3% | 3.16 | 1 / 29 |
intestine | 0% | 0 | 0 / 966 | 3% | 7.28 | 17 / 527 |
peripheral blood | 1% | 22.63 | 12 / 929 | 0% | 0 | 0 / 0 |
stomach | 1% | 18.60 | 2 / 359 | 1% | 0.09 | 2 / 286 |
prostate | 1% | 24.76 | 2 / 245 | 0% | 0.06 | 2 / 502 |
kidney | 0% | 0 | 0 / 89 | 1% | 0.39 | 7 / 901 |
adipose | 0% | 13.48 | 6 / 1204 | 0% | 0 | 0 / 0 |
ovary | 0% | 0 | 0 / 180 | 0% | 0.21 | 2 / 430 |
muscle | 0% | 6.39 | 2 / 803 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 0% | 0.03 | 1 / 406 |
blood vessel | 0% | 3.25 | 1 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
brain | 0% | 0 | 0 / 2642 | 0% | 0 | 0 / 705 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
GO_0030216 | Biological process | keratinocyte differentiation |
GO_0031424 | Biological process | keratinization |
GO_0018149 | Biological process | peptide cross-linking |
GO_0018153 | Biological process | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine |
GO_0010224 | Biological process | response to UV-B |
GO_0001533 | Cellular component | cornified envelope |
GO_0005813 | Cellular component | centrosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0016604 | Cellular component | nuclear body |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
Gene name | IVL |
Protein name | Involucrin |
Synonyms | |
Description | FUNCTION: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. |
Accessions | ENST00000368764.4 P07476 |