ITIH1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030212Biological processhyaluronan metabolic process
GO_0072562Cellular componentblood microparticle
GO_0070062Cellular componentextracellular exosome
GO_0005576Cellular componentextracellular region
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity
GO_0005509Molecular functioncalcium ion binding
GO_0030246Molecular functioncarbohydrate binding
GO_0005540Molecular functionhyaluronic acid binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameITIH1
Protein nameInter-alpha-trypsin inhibitor heavy chain H1 (ITI heavy chain H1) (ITI-HC1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP)
Inter-alpha-trypsin inhibitor heavy chain 1
SynonymsIGHEP1
DescriptionFUNCTION: May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.; FUNCTION: Contains a potential peptide which could stimulate a broad spectrum of phagocytotic cells.

AccessionsENST00000480409.1
B5MCP1
ENST00000428133.5
ENST00000405128.3
F8WAS2
H7C0N0
ENST00000484844.2
H7C5I0
P19827
ENST00000273283.7 [P19827-1]
ENST00000537050.5 [P19827-3]