Insufficient scRNA-seq data for expression of ISX at single-cell level.
Insufficient scRNA-seq data for expression of ISX at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 75% | 2217.52 | 728 / 966 | 69% | 15.89 | 364 / 527 |
| prostate | 73% | 30.00 | 178 / 245 | 52% | 3.39 | 259 / 502 |
| kidney | 67% | 22.39 | 60 / 89 | 0% | 0.01 | 2 / 901 |
| stomach | 1% | 0.53 | 5 / 359 | 52% | 12.40 | 150 / 286 |
| liver | 1% | 0.83 | 3 / 226 | 39% | 5.73 | 158 / 406 |
| bladder | 0% | 0 | 0 / 21 | 22% | 4.71 | 109 / 504 |
| peripheral blood | 16% | 22.98 | 152 / 929 | 0% | 0 | 0 / 0 |
| skin | 14% | 2.12 | 258 / 1809 | 0% | 0.02 | 2 / 472 |
| esophagus | 1% | 0.65 | 13 / 1445 | 13% | 2.45 | 24 / 183 |
| pancreas | 8% | 0.79 | 25 / 328 | 3% | 1.12 | 6 / 178 |
| lung | 1% | 0.15 | 4 / 578 | 7% | 1.01 | 80 / 1155 |
| uterus | 2% | 0.62 | 3 / 170 | 2% | 0.18 | 11 / 459 |
| breast | 3% | 9.98 | 12 / 459 | 2% | 0.34 | 17 / 1118 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.14 | 1 / 29 |
| ovary | 2% | 0.18 | 3 / 180 | 0% | 0.02 | 2 / 430 |
| muscle | 2% | 0.20 | 15 / 803 | 0% | 0 | 0 / 0 |
| spleen | 1% | 0.19 | 3 / 241 | 0% | 0 | 0 / 0 |
| thymus | 1% | 0.10 | 7 / 653 | 0% | 0.02 | 1 / 605 |
| heart | 1% | 0.11 | 9 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 0.13 | 10 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 1% | 0.17 | 8 / 1204 | 0% | 0 | 0 / 0 |
| brain | 0% | 0.04 | 7 / 2642 | 0% | 0 | 0 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Gene name | ISX |
| Protein name | Intestine-specific homeobox (RAX-like homeobox) |
| Synonyms | RAXLX |
| Description | FUNCTION: Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine (By similarity). . |
| Accessions | Q2M1V0 ENST00000404699.7 ENST00000308700.6 |