I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 6 studies | 41% ± 23% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 6 studies | 41% ± 23% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 34% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 1930.46 | 245 / 245 | 98% | 4.85 | 492 / 502 |
| brain | 99% | 6359.30 | 2623 / 2642 | 99% | 11.15 | 696 / 705 |
| kidney | 100% | 1868.58 | 89 / 89 | 98% | 5.23 | 880 / 901 |
| pancreas | 100% | 1064.76 | 327 / 328 | 98% | 5.17 | 174 / 178 |
| adrenal gland | 100% | 2290.14 | 258 / 258 | 97% | 11.39 | 224 / 230 |
| breast | 100% | 1367.44 | 458 / 459 | 97% | 7.84 | 1086 / 1118 |
| ovary | 97% | 1001.45 | 175 / 180 | 98% | 7.60 | 423 / 430 |
| intestine | 100% | 1709.96 | 966 / 966 | 93% | 4.38 | 490 / 527 |
| bladder | 100% | 1570.62 | 21 / 21 | 92% | 4.96 | 466 / 504 |
| lung | 99% | 1482.47 | 571 / 578 | 94% | 4.99 | 1080 / 1155 |
| uterus | 100% | 1673.47 | 170 / 170 | 92% | 4.87 | 423 / 459 |
| thymus | 100% | 1485.14 | 651 / 653 | 92% | 4.46 | 558 / 605 |
| esophagus | 100% | 1333.42 | 1438 / 1445 | 91% | 4.66 | 166 / 183 |
| stomach | 96% | 1007.24 | 345 / 359 | 92% | 4.64 | 264 / 286 |
| skin | 100% | 1490.24 | 1802 / 1809 | 85% | 3.82 | 400 / 472 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.05 | 1 / 1 |
| blood vessel | 99% | 1413.01 | 1323 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 99% | 3311.62 | 795 / 803 | 0% | 0 | 0 / 0 |
| adipose | 97% | 1203.29 | 1173 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 94% | 819.52 | 226 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 3.78 | 40 / 45 |
| eye | 0% | 0 | 0 / 0 | 88% | 3.02 | 70 / 80 |
| heart | 83% | 705.66 | 717 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 38% | 1.03 | 11 / 29 |
| peripheral blood | 22% | 166.71 | 206 / 929 | 0% | 0 | 0 / 0 |
| liver | 2% | 13.89 | 4 / 226 | 9% | 0.33 | 36 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0098696 | Biological process | regulation of neurotransmitter receptor localization to postsynaptic specialization membrane |
| GO_0051968 | Biological process | positive regulation of synaptic transmission, glutamatergic |
| GO_0030036 | Biological process | actin cytoskeleton organization |
| GO_1900454 | Biological process | positive regulation of long-term synaptic depression |
| GO_0032012 | Biological process | regulation of ARF protein signal transduction |
| GO_0050804 | Biological process | modulation of chemical synaptic transmission |
| GO_0051965 | Biological process | positive regulation of synapse assembly |
| GO_0098685 | Cellular component | Schaffer collateral - CA1 synapse |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
| Gene name | IQSEC2 |
| Protein name | IQ motif and Sec7 domain ArfGEF 2 Alternative protein IQSEC2 IQ motif and SEC7 domain-containing protein 2 |
| Synonyms | KIAA0522 |
| Description | FUNCTION: Is a guanine nucleotide exchange factor for the ARF GTP-binding proteins. . |
| Accessions | ENST00000638630.1 ENST00000638521.1 ENST00000675731.1 A0A1W2PPE7 ENST00000485377.5 Q5JU85 A0A1W2PR18 L8E757 ENST00000639796.1 ENST00000706952.1 ENST00000640005.1 ENST00000638583.1 ENST00000674510.1 [Q5JU85-2] A0A6Q8PFR7 A0A1W2PRJ5 ENST00000498281.2 ENST00000639485.1 ENST00000638869.1 A0A1W2PPU7 ENST00000640694.1 ENST00000642864.1 [Q5JU85-2] A0A1W2PQ34 A0A1W2PR28 A0A1W2PPR2 ENST00000375365.2 [Q5JU85-3] A0A1W2PQP8 A0A6Q8PG99 A0A1W2PR10 A0A9L9PY69 ENST00000675719.1 ENST00000639642.1 A0A1W2PQS2 ENST00000639161.2 [Q5JU85-4] A0A1W2PPD3 |
