Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 5 studies | 29% ± 16% | |
endothelial cell | 4 studies | 18% ± 3% | |
epithelial cell | 4 studies | 20% ± 5% | |
GABAergic neuron | 4 studies | 30% ± 12% | |
glutamatergic neuron | 4 studies | 37% ± 11% | |
oligodendrocyte precursor cell | 4 studies | 27% ± 6% | |
club cell | 3 studies | 23% ± 5% | |
ciliated cell | 3 studies | 23% ± 7% | |
type II pneumocyte | 3 studies | 21% ± 4% | |
interneuron | 3 studies | 36% ± 15% | |
neuron | 3 studies | 21% ± 3% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 28% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 729.42 | 1445 / 1445 | 100% | 9.18 | 183 / 183 |
intestine | 100% | 724.53 | 966 / 966 | 100% | 8.98 | 527 / 527 |
lung | 100% | 756.35 | 578 / 578 | 100% | 8.62 | 1155 / 1155 |
stomach | 100% | 586.94 | 359 / 359 | 100% | 9.30 | 286 / 286 |
breast | 100% | 937.65 | 459 / 459 | 100% | 13.69 | 1116 / 1118 |
prostate | 100% | 932.16 | 245 / 245 | 100% | 11.37 | 501 / 502 |
ovary | 100% | 540.71 | 180 / 180 | 100% | 7.71 | 429 / 430 |
brain | 100% | 505.27 | 2635 / 2642 | 100% | 13.16 | 705 / 705 |
uterus | 100% | 726.16 | 170 / 170 | 100% | 8.37 | 457 / 459 |
thymus | 100% | 968.90 | 653 / 653 | 100% | 10.92 | 602 / 605 |
pancreas | 100% | 385.18 | 328 / 328 | 99% | 7.61 | 177 / 178 |
bladder | 100% | 672.29 | 21 / 21 | 99% | 8.10 | 498 / 504 |
skin | 100% | 767.49 | 1809 / 1809 | 98% | 9.48 | 464 / 472 |
kidney | 100% | 760.19 | 89 / 89 | 98% | 6.48 | 880 / 901 |
liver | 100% | 458.97 | 226 / 226 | 97% | 5.71 | 394 / 406 |
adrenal gland | 100% | 590.30 | 258 / 258 | 97% | 6.77 | 222 / 230 |
adipose | 100% | 804.30 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 841.31 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 6.69 | 29 / 29 |
muscle | 100% | 841.32 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 630.73 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 8.66 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.82 | 1 / 1 |
heart | 99% | 614.14 | 849 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 6.11 | 77 / 80 |
peripheral blood | 93% | 562.90 | 862 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0034243 | Biological process | regulation of transcription elongation by RNA polymerase II |
GO_0016180 | Biological process | snRNA processing |
GO_0034472 | Biological process | snRNA 3'-end processing |
GO_0032039 | Cellular component | integrator complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | INTS12 |
Protein name | Integrator complex subunit 12 Integrator complex subunit 12 (Int12) (PHD finger protein 22) |
Synonyms | SBBI22 PHF22 |
Description | FUNCTION: Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes . Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex . . |
Accessions | ENST00000340139.10 D6R9Y5 ENST00000433009.1 ENST00000451321.6 ENST00000515819.1 ENST00000416543.5 ENST00000420368.6 D6R9W3 A0A1B0GX90 Q96CB8 ENST00000510876.1 C9J0M6 ENST00000394735.5 ENST00000503746.5 C9JDP3 E9PGI3 |