ING1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ING1 at tissue level.

III. Associated gene sets

GO_0030336Biological processnegative regulation of cell migration
GO_1902455Biological processnegative regulation of stem cell population maintenance
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0043067Biological processregulation of programmed cell death
GO_1902459Biological processpositive regulation of stem cell population maintenance
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0030512Biological processnegative regulation of transforming growth factor beta receptor signaling pathway
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006606Biological processprotein import into nucleus
GO_0030308Biological processnegative regulation of cell growth
GO_0070822Cellular componentSin3-type complex
GO_0005634Cellular componentnucleus
GO_0035064Molecular functionmethylated histone binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameING1
Protein nameInhibitor of growth protein
Inhibitor of growth family member 1
Inhibitor of growth protein 1
SynonymshCG_1774813
DescriptionFUNCTION: Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene. .

FUNCTION: Component of an histone acetyltransferase complex. .

AccessionsENST00000464141.1
ENST00000375775.4 [Q9UK53-3]
A0A087WXF7
ENST00000338450.7 [Q9UK53-4]
Q9UK53
ENST00000375774.3
A0A0C4DFW2
ENST00000333219.9 [Q9UK53-2]