Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 5 studies | 20% ± 3% | |
| endothelial cell | 4 studies | 17% ± 0% | |
| pericyte | 3 studies | 34% ± 15% | |
| epithelial cell | 3 studies | 35% ± 13% | |
| fibroblast | 3 studies | 26% ± 9% |
Insufficient scRNA-seq data for expression of ING1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 909.37 | 1445 / 1445 | 100% | 11.44 | 183 / 183 |
| ovary | 100% | 2224.47 | 180 / 180 | 100% | 13.67 | 430 / 430 |
| lung | 100% | 1270.57 | 578 / 578 | 100% | 11.47 | 1154 / 1155 |
| intestine | 100% | 1251.20 | 966 / 966 | 100% | 13.93 | 526 / 527 |
| bladder | 100% | 1025.81 | 21 / 21 | 100% | 13.15 | 503 / 504 |
| uterus | 100% | 1355.35 | 170 / 170 | 100% | 13.73 | 458 / 459 |
| brain | 100% | 849.18 | 2636 / 2642 | 100% | 13.46 | 705 / 705 |
| breast | 100% | 1087.76 | 459 / 459 | 100% | 15.92 | 1115 / 1118 |
| stomach | 100% | 817.78 | 359 / 359 | 100% | 13.80 | 285 / 286 |
| prostate | 100% | 1247.74 | 245 / 245 | 100% | 19.54 | 500 / 502 |
| pancreas | 100% | 508.22 | 327 / 328 | 99% | 10.80 | 176 / 178 |
| thymus | 100% | 844.81 | 653 / 653 | 98% | 9.84 | 595 / 605 |
| skin | 100% | 854.60 | 1808 / 1809 | 97% | 11.02 | 459 / 472 |
| liver | 100% | 898.03 | 226 / 226 | 95% | 8.23 | 387 / 406 |
| kidney | 100% | 849.98 | 89 / 89 | 95% | 8.20 | 856 / 901 |
| adrenal gland | 100% | 636.75 | 258 / 258 | 91% | 6.33 | 209 / 230 |
| adipose | 100% | 1212.41 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1316.47 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 12.09 | 29 / 29 |
| spleen | 100% | 1518.85 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 14.68 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 3.86 | 1 / 1 |
| peripheral blood | 99% | 1307.77 | 924 / 929 | 0% | 0 | 0 / 0 |
| muscle | 99% | 572.21 | 796 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 562.42 | 843 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 89% | 5.35 | 71 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0030336 | Biological process | negative regulation of cell migration |
| GO_1902455 | Biological process | negative regulation of stem cell population maintenance |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0043067 | Biological process | regulation of programmed cell death |
| GO_1902459 | Biological process | positive regulation of stem cell population maintenance |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0030512 | Biological process | negative regulation of transforming growth factor beta receptor signaling pathway |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0006606 | Biological process | protein import into nucleus |
| GO_0030308 | Biological process | negative regulation of cell growth |
| GO_0070822 | Cellular component | Sin3-type complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0035064 | Molecular function | methylated histone binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | ING1 |
| Protein name | Inhibitor of growth protein Inhibitor of growth family member 1 Inhibitor of growth protein 1 |
| Synonyms | hCG_1774813 |
| Description | FUNCTION: Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene. . FUNCTION: Component of an histone acetyltransferase complex. . |
| Accessions | ENST00000464141.1 ENST00000375775.4 [Q9UK53-3] A0A087WXF7 ENST00000338450.7 [Q9UK53-4] Q9UK53 ENST00000375774.3 A0A0C4DFW2 ENST00000333219.9 [Q9UK53-2] |