Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 8 studies | 25% ± 6% | |
fibroblast | 8 studies | 24% ± 6% | |
epithelial cell | 7 studies | 29% ± 9% | |
astrocyte | 6 studies | 30% ± 12% | |
oligodendrocyte | 5 studies | 29% ± 7% | |
neuron | 4 studies | 25% ± 10% | |
plasma cell | 4 studies | 29% ± 10% | |
adipocyte | 4 studies | 31% ± 6% | |
ciliated cell | 4 studies | 23% ± 5% | |
basal cell | 4 studies | 27% ± 12% | |
abnormal cell | 4 studies | 29% ± 9% | |
goblet cell | 4 studies | 28% ± 13% | |
glutamatergic neuron | 4 studies | 44% ± 26% | |
interneuron | 4 studies | 41% ± 22% | |
GABAergic neuron | 4 studies | 39% ± 23% | |
CD4-positive, alpha-beta T cell | 3 studies | 20% ± 6% | |
lymphocyte | 3 studies | 20% ± 3% | |
muscle cell | 3 studies | 21% ± 5% | |
B cell | 3 studies | 19% ± 3% | |
dendritic cell | 3 studies | 22% ± 4% | |
connective tissue cell | 3 studies | 24% ± 8% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 33% ± 9% | |
pericyte | 3 studies | 24% ± 7% | |
erythrocyte | 3 studies | 31% ± 12% | |
transit amplifying cell | 3 studies | 38% ± 16% | |
erythroblast | 3 studies | 30% ± 10% | |
microglial cell | 3 studies | 24% ± 6% | |
oligodendrocyte precursor cell | 3 studies | 37% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 6388.97 | 1445 / 1445 | 100% | 93.92 | 183 / 183 |
ovary | 100% | 5519.41 | 180 / 180 | 100% | 54.12 | 430 / 430 |
stomach | 100% | 6603.51 | 359 / 359 | 100% | 77.71 | 286 / 286 |
intestine | 100% | 5911.80 | 965 / 966 | 100% | 79.73 | 526 / 527 |
breast | 100% | 6352.77 | 459 / 459 | 100% | 79.03 | 1114 / 1118 |
lung | 100% | 6888.61 | 576 / 578 | 100% | 65.95 | 1154 / 1155 |
pancreas | 100% | 5088.55 | 328 / 328 | 99% | 41.02 | 177 / 178 |
prostate | 100% | 6102.53 | 245 / 245 | 99% | 56.35 | 498 / 502 |
thymus | 100% | 7200.85 | 653 / 653 | 99% | 49.76 | 598 / 605 |
uterus | 100% | 7937.11 | 170 / 170 | 99% | 59.10 | 453 / 459 |
bladder | 100% | 6965.48 | 21 / 21 | 99% | 59.94 | 497 / 504 |
skin | 100% | 11905.47 | 1809 / 1809 | 98% | 70.08 | 461 / 472 |
kidney | 100% | 5194.92 | 89 / 89 | 96% | 43.38 | 867 / 901 |
brain | 95% | 4056.42 | 2518 / 2642 | 100% | 54.32 | 703 / 705 |
adrenal gland | 100% | 7764.52 | 258 / 258 | 91% | 41.93 | 210 / 230 |
liver | 100% | 3903.75 | 225 / 226 | 86% | 25.83 | 350 / 406 |
adipose | 100% | 6162.69 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 58.97 | 29 / 29 |
muscle | 100% | 8259.30 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 5915.09 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 66.79 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 13.76 | 1 / 1 |
blood vessel | 100% | 6222.05 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 94% | 4686.49 | 808 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 91% | 37.70 | 73 / 80 |
peripheral blood | 51% | 4695.78 | 470 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0106074 | Biological process | aminoacyl-tRNA metabolism involved in translational fidelity |
GO_0006428 | Biological process | isoleucyl-tRNA aminoacylation |
GO_0006418 | Biological process | tRNA aminoacylation for protein translation |
GO_0001649 | Biological process | osteoblast differentiation |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0017101 | Cellular component | aminoacyl-tRNA synthetase multienzyme complex |
GO_0016020 | Cellular component | membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0000049 | Molecular function | tRNA binding |
GO_0051020 | Molecular function | GTPase binding |
GO_0004822 | Molecular function | isoleucine-tRNA ligase activity |
GO_0002161 | Molecular function | aminoacyl-tRNA editing activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | IARS1 |
Protein name | Isoleucyl-tRNA synthetase 1 IARS protein Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS) isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) |
Synonyms | IARS |
Description | FUNCTION: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. . |
Accessions | A0A804HJN6 A0A804HKU1 A0A804HK69 ENST00000443024.7 ENST00000683469.1 P41252 ENST00000443024 A0A804HHW9 ENST00000375643.7 ENST00000684757.1 A0A804HLB4 ENST00000683119.1 ENST00000683679.1 ENST00000684557.1 ENST00000707248.1 Q6P0M4 A0A0D9SFC1 A0A804HIV9 A0A804HJ36 ENST00000627121.3 ENST00000447699.7 A0A804HL54 ENST00000683192.1 ENST00000683495.1 ENST00000682578.1 ENST00000682533.1 ENST00000683537.1 A0A804HKW6 ENST00000684542.1 ENST00000683565.1 ENST00000683817.1 A0A0A0MSX9 ENST00000707249.1 ENST00000682756.1 Q7L4K8 A0A804HIG2 J3KR24 ENST00000707251.1 ENST00000684445.1 |