IARS1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0106074Biological processaminoacyl-tRNA metabolism involved in translational fidelity
GO_0006428Biological processisoleucyl-tRNA aminoacylation
GO_0006418Biological processtRNA aminoacylation for protein translation
GO_0001649Biological processosteoblast differentiation
GO_0070062Cellular componentextracellular exosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0017101Cellular componentaminoacyl-tRNA synthetase multienzyme complex
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0000049Molecular functiontRNA binding
GO_0051020Molecular functionGTPase binding
GO_0004822Molecular functionisoleucine-tRNA ligase activity
GO_0002161Molecular functionaminoacyl-tRNA editing activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameIARS1
Protein nameIsoleucyl-tRNA synthetase 1
IARS protein
Isoleucine--tRNA ligase, cytoplasmic (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IRS) (IleRS)
isoleucine--tRNA ligase (EC 6.1.1.5) (Isoleucyl-tRNA synthetase)
SynonymsIARS
DescriptionFUNCTION: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. .

AccessionsA0A804HJN6
A0A804HKU1
A0A804HK69
ENST00000443024.7
ENST00000683469.1
P41252
ENST00000443024
A0A804HHW9
ENST00000375643.7
ENST00000684757.1
A0A804HLB4
ENST00000683119.1
ENST00000683679.1
ENST00000684557.1
ENST00000707248.1
Q6P0M4
A0A0D9SFC1
A0A804HIV9
A0A804HJ36
ENST00000627121.3
ENST00000447699.7
A0A804HL54
ENST00000683192.1
ENST00000683495.1
ENST00000682578.1
ENST00000682533.1
ENST00000683537.1
A0A804HKW6
ENST00000684542.1
ENST00000683565.1
ENST00000683817.1
A0A0A0MSX9
ENST00000707249.1
ENST00000682756.1
Q7L4K8
A0A804HIG2
J3KR24
ENST00000707251.1
ENST00000684445.1