Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell of lymphatic vessel | 12 studies | 31% ± 14% | |
endothelial cell | 12 studies | 29% ± 15% | |
fibroblast | 11 studies | 26% ± 6% | |
oligodendrocyte | 8 studies | 33% ± 12% | |
microglial cell | 7 studies | 21% ± 5% | |
pericyte | 7 studies | 23% ± 6% | |
non-classical monocyte | 5 studies | 22% ± 9% | |
adipocyte | 5 studies | 23% ± 2% | |
macrophage | 5 studies | 25% ± 3% | |
smooth muscle cell | 5 studies | 22% ± 3% | |
epithelial cell | 4 studies | 22% ± 6% | |
retinal pigment epithelial cell | 4 studies | 44% ± 8% | |
dendritic cell | 4 studies | 23% ± 6% | |
glutamatergic neuron | 4 studies | 25% ± 7% | |
classical monocyte | 3 studies | 17% ± 0% | |
retinal bipolar neuron | 3 studies | 22% ± 4% | |
rod bipolar cell | 3 studies | 47% ± 10% | |
adventitial cell | 3 studies | 21% ± 7% | |
alveolar macrophage | 3 studies | 27% ± 7% | |
GABAergic neuron | 3 studies | 25% ± 5% | |
astrocyte | 3 studies | 31% ± 15% | |
myoepithelial cell | 3 studies | 32% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 3746.77 | 577 / 578 | 95% | 10.11 | 1101 / 1155 |
skin | 96% | 3395.50 | 1743 / 1809 | 96% | 17.49 | 453 / 472 |
esophagus | 100% | 2684.03 | 1445 / 1445 | 91% | 11.11 | 167 / 183 |
uterus | 100% | 2651.94 | 170 / 170 | 82% | 6.28 | 378 / 459 |
breast | 100% | 3600.74 | 459 / 459 | 75% | 4.30 | 842 / 1118 |
pancreas | 87% | 777.51 | 285 / 328 | 87% | 4.85 | 154 / 178 |
brain | 76% | 878.38 | 2001 / 2642 | 95% | 8.38 | 669 / 705 |
bladder | 100% | 2080.71 | 21 / 21 | 60% | 4.06 | 300 / 504 |
adrenal gland | 97% | 1029.28 | 250 / 258 | 63% | 3.46 | 144 / 230 |
prostate | 97% | 1577.26 | 238 / 245 | 58% | 1.92 | 292 / 502 |
thymus | 99% | 1923.22 | 648 / 653 | 53% | 1.85 | 321 / 605 |
kidney | 79% | 738.71 | 70 / 89 | 74% | 3.42 | 663 / 901 |
intestine | 96% | 2136.60 | 926 / 966 | 42% | 2.13 | 223 / 527 |
liver | 93% | 799.31 | 210 / 226 | 45% | 1.69 | 181 / 406 |
ovary | 99% | 1469.52 | 179 / 180 | 36% | 1.19 | 153 / 430 |
stomach | 73% | 989.82 | 262 / 359 | 60% | 3.42 | 171 / 286 |
adipose | 100% | 4007.61 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3421.81 | 1335 / 1335 | 0% | 0 | 0 / 0 |
muscle | 100% | 3404.76 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2167.33 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 98% | 1655.87 | 848 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 7.06 | 28 / 29 |
tonsil | 0% | 0 | 0 / 0 | 89% | 6.99 | 40 / 45 |
eye | 0% | 0 | 0 / 0 | 88% | 7.25 | 70 / 80 |
peripheral blood | 42% | 1315.61 | 387 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0046854 | Biological process | phosphatidylinositol phosphate biosynthetic process |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0042552 | Biological process | myelination |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0043005 | Cellular component | neuron projection |
GO_0005515 | Molecular function | protein binding |
Gene name | HYCC1 |
Protein name | Hyccin PI4KA lipid kinase complex subunit 1 Hyccin (Down-regulated by CTNNB1 protein A) Family with sequence similarity 126 member A isoform 3 |
Synonyms | DRCTNNB1A FAM126A |
Description | FUNCTION: Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane . The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis . HYCC1 plays a key role in oligodendrocytes formation, a cell type with expanded plasma membrane that requires generation of PtdIns(4)P . Its role in oligodendrocytes formation probably explains its importance in myelination of the central and peripheral nervous system . May also have a role in the beta-catenin/Lef signaling pathway (Probable). . |
Accessions | ENST00000681079.1 ENST00000679789.1 ENST00000432176.7 [Q9BYI3-1] A0A7P0T943 A0A7P0TAP6 A0A7P0T8Q9 B8ZZA2 Q9BYI3 A0A7P0Z4L0 ENST00000409763.1 ENST00000681402.1 A0A7P0T8K2 ENST00000409923.5 [Q9BYI3-3] A0A7P0TBJ9 ENST00000681766.1 ENST00000679826.1 ENST00000440481.6 A0A0S2Z6M9 ENST00000681237.1 H7C0W7 |