I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 25% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| GABAergic neuron | 3 studies | 25% ± 5% |
Insufficient scRNA-seq data for expression of HTR7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 149.67 | 21 / 21 | 36% | 2.73 | 183 / 504 |
| esophagus | 72% | 49.31 | 1043 / 1445 | 44% | 3.15 | 81 / 183 |
| breast | 84% | 53.53 | 386 / 459 | 29% | 0.58 | 329 / 1118 |
| lung | 78% | 34.94 | 452 / 578 | 35% | 2.32 | 405 / 1155 |
| skin | 89% | 158.37 | 1611 / 1809 | 19% | 0.91 | 90 / 472 |
| stomach | 96% | 88.27 | 345 / 359 | 6% | 0.12 | 18 / 286 |
| intestine | 90% | 55.39 | 866 / 966 | 5% | 0.13 | 26 / 527 |
| brain | 68% | 74.16 | 1785 / 2642 | 27% | 0.49 | 188 / 705 |
| blood vessel | 90% | 128.34 | 1206 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 79% | 36.30 | 193 / 245 | 7% | 0.10 | 37 / 502 |
| adipose | 80% | 57.99 | 962 / 1204 | 0% | 0 | 0 / 0 |
| uterus | 36% | 11.95 | 62 / 170 | 40% | 2.95 | 183 / 459 |
| spleen | 69% | 29.68 | 167 / 241 | 0% | 0 | 0 / 0 |
| muscle | 66% | 71.39 | 527 / 803 | 0% | 0 | 0 / 0 |
| adrenal gland | 34% | 10.67 | 87 / 258 | 21% | 0.85 | 48 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 53% | 4.09 | 24 / 45 |
| thymus | 47% | 16.51 | 307 / 653 | 6% | 0.27 | 37 / 605 |
| kidney | 18% | 6.53 | 16 / 89 | 33% | 0.69 | 299 / 901 |
| ovary | 26% | 9.77 | 46 / 180 | 6% | 0.08 | 25 / 430 |
| pancreas | 9% | 2.73 | 30 / 328 | 20% | 0.72 | 36 / 178 |
| heart | 27% | 8.43 | 231 / 861 | 0% | 0 | 0 / 0 |
| liver | 18% | 6.73 | 41 / 226 | 2% | 0.08 | 8 / 406 |
| peripheral blood | 17% | 5.76 | 159 / 929 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006939 | Biological process | smooth muscle contraction |
| GO_0008015 | Biological process | blood circulation |
| GO_0042310 | Biological process | vasoconstriction |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0098664 | Biological process | G protein-coupled serotonin receptor signaling pathway |
| GO_0007623 | Biological process | circadian rhythm |
| GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
| GO_0032588 | Cellular component | trans-Golgi network membrane |
| GO_0030425 | Cellular component | dendrite |
| GO_0045202 | Cellular component | synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0004993 | Molecular function | G protein-coupled serotonin receptor activity |
| GO_0030594 | Molecular function | neurotransmitter receptor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HTR7 |
| Protein name | 5-hydroxytryptamine receptor 7 (5-HT-7) (5-HT7) (5-HT-X) (Serotonin receptor 7) |
| Synonyms | |
| Description | FUNCTION: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
| Accessions | ENST00000371719.2 [P34969-3] ENST00000336152.8 [P34969-1] P34969 ENST00000277874.10 [P34969-2] |
