Insufficient scRNA-seq data for expression of HTR3D at single-cell level.
Insufficient scRNA-seq data for expression of HTR3D at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 28% | 1.57 | 25 / 89 | 0% | 0.01 | 3 / 901 |
lung | 27% | 0.60 | 154 / 578 | 0% | 0.02 | 4 / 1155 |
adipose | 22% | 0.47 | 269 / 1204 | 0% | 0 | 0 / 0 |
brain | 22% | 0.42 | 578 / 2642 | 0% | 0 | 0 / 705 |
prostate | 19% | 0.28 | 47 / 245 | 0% | 0.01 | 2 / 502 |
bladder | 19% | 0.24 | 4 / 21 | 0% | 0 | 0 / 504 |
muscle | 18% | 0.31 | 142 / 803 | 0% | 0 | 0 / 0 |
thymus | 17% | 0.30 | 114 / 653 | 0% | 0 | 0 / 605 |
adrenal gland | 17% | 0.24 | 45 / 258 | 0% | 0 | 0 / 230 |
breast | 17% | 0.30 | 79 / 459 | 0% | 0 | 0 / 1118 |
uterus | 17% | 0.29 | 29 / 170 | 0% | 0 | 0 / 459 |
intestine | 16% | 0.23 | 152 / 966 | 1% | 0.01 | 3 / 527 |
skin | 15% | 0.25 | 277 / 1809 | 0% | 0 | 0 / 472 |
spleen | 15% | 0.25 | 36 / 241 | 0% | 0 | 0 / 0 |
esophagus | 13% | 0.21 | 195 / 1445 | 1% | 0.02 | 1 / 183 |
heart | 13% | 0.20 | 115 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 13% | 0.23 | 178 / 1335 | 0% | 0 | 0 / 0 |
ovary | 13% | 0.21 | 23 / 180 | 0% | 0 | 0 / 430 |
stomach | 11% | 0.14 | 39 / 359 | 1% | 0.05 | 3 / 286 |
liver | 11% | 0.18 | 24 / 226 | 0% | 0 | 0 / 406 |
peripheral blood | 9% | 0.13 | 88 / 929 | 0% | 0 | 0 / 0 |
pancreas | 7% | 0.09 | 24 / 328 | 0% | 0 | 0 / 178 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0034220 | Biological process | monoatomic ion transmembrane transport |
GO_0042391 | Biological process | regulation of membrane potential |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0007210 | Biological process | serotonin receptor signaling pathway |
GO_0098662 | Biological process | inorganic cation transmembrane transport |
GO_0060079 | Biological process | excitatory postsynaptic potential |
GO_1902495 | Cellular component | transmembrane transporter complex |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_1904602 | Cellular component | serotonin-activated cation-selective channel complex |
GO_0045202 | Cellular component | synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0043005 | Cellular component | neuron projection |
GO_0005231 | Molecular function | excitatory extracellular ligand-gated monoatomic ion channel activity |
GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
GO_0022850 | Molecular function | serotonin-gated monoatomic cation channel activity |
GO_0005515 | Molecular function | protein binding |
Gene name | HTR3D |
Protein name | 5-hydroxytryptamine receptor 3D (5-HT3-D) (5-HT3D) (Serotonin receptor 3D) 5-hydroxytryptamine receptor 3D |
Synonyms | |
Description | FUNCTION: Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. . |
Accessions | ENST00000382489.3 [Q70Z44-1] ENST00000334128.6 ENST00000428798.7 [Q70Z44-4] Q70Z44 ENST00000453435.1 [Q70Z44-3] F6WC43 |