Insufficient scRNA-seq data for expression of HTR3C at single-cell level.
Insufficient scRNA-seq data for expression of HTR3C at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 98% | 223.60 | 565 / 578 | 4% | 0.22 | 48 / 1155 |
| thymus | 77% | 10.40 | 504 / 653 | 1% | 0.10 | 8 / 605 |
| prostate | 58% | 7.20 | 141 / 245 | 3% | 0.21 | 14 / 502 |
| intestine | 51% | 8.65 | 493 / 966 | 5% | 0.25 | 27 / 527 |
| breast | 42% | 3.44 | 192 / 459 | 0% | 0.00 | 3 / 1118 |
| adipose | 39% | 3.00 | 465 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 33% | 1.87 | 118 / 359 | 6% | 0.10 | 16 / 286 |
| uterus | 29% | 1.85 | 50 / 170 | 1% | 0.02 | 4 / 459 |
| ovary | 23% | 1.39 | 41 / 180 | 3% | 0.39 | 13 / 430 |
| esophagus | 22% | 1.35 | 317 / 1445 | 4% | 0.14 | 7 / 183 |
| pancreas | 7% | 0.35 | 24 / 328 | 16% | 0.54 | 29 / 178 |
| bladder | 19% | 0.76 | 4 / 21 | 4% | 0.43 | 22 / 504 |
| skin | 19% | 1.29 | 339 / 1809 | 3% | 0.05 | 12 / 472 |
| kidney | 20% | 0.90 | 18 / 89 | 0% | 0.01 | 3 / 901 |
| adrenal gland | 19% | 0.88 | 50 / 258 | 0% | 0 | 0 / 230 |
| blood vessel | 9% | 0.64 | 114 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 5% | 0.31 | 11 / 241 | 0% | 0 | 0 / 0 |
| brain | 4% | 0.19 | 107 / 2642 | 0% | 0 | 0 / 705 |
| liver | 3% | 0.12 | 6 / 226 | 0% | 0.02 | 2 / 406 |
| heart | 3% | 0.46 | 27 / 861 | 0% | 0 | 0 / 0 |
| muscle | 3% | 0.15 | 23 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 2% | 0.07 | 17 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_0042391 | Biological process | regulation of membrane potential |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0007210 | Biological process | serotonin receptor signaling pathway |
| GO_0098662 | Biological process | inorganic cation transmembrane transport |
| GO_0060079 | Biological process | excitatory postsynaptic potential |
| GO_1902495 | Cellular component | transmembrane transporter complex |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_1904602 | Cellular component | serotonin-activated cation-selective channel complex |
| GO_0045202 | Cellular component | synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043005 | Cellular component | neuron projection |
| GO_0005231 | Molecular function | excitatory extracellular ligand-gated monoatomic ion channel activity |
| GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
| GO_0022850 | Molecular function | serotonin-gated monoatomic cation channel activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HTR3C |
| Protein name | 5-hydroxytryptamine receptor 3C (5-HT3-C) (5-HT3C) (Serotonin receptor 3C) |
| Synonyms | |
| Description | FUNCTION: Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons. . |
| Accessions | Q8WXA8 ENST00000318351.2 |