Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| mast cell | 14 studies | 33% ± 17% | |
| glutamatergic neuron | 6 studies | 31% ± 14% | |
| astrocyte | 5 studies | 26% ± 5% | |
| retinal cone cell | 4 studies | 21% ± 5% | |
| GABAergic neuron | 4 studies | 28% ± 8% | |
| endothelial cell | 3 studies | 27% ± 4% | |
| microglial cell | 3 studies | 21% ± 5% | |
| retina horizontal cell | 3 studies | 19% ± 1% | |
| interneuron | 3 studies | 27% ± 9% | |
| neuron | 3 studies | 20% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 5 studies | 27% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 4495.96 | 2636 / 2642 | 100% | 54.45 | 702 / 705 |
| ovary | 100% | 3574.09 | 180 / 180 | 99% | 76.21 | 427 / 430 |
| prostate | 100% | 4183.53 | 245 / 245 | 99% | 38.51 | 497 / 502 |
| breast | 100% | 2460.19 | 458 / 459 | 99% | 54.04 | 1109 / 1118 |
| pancreas | 100% | 2455.16 | 328 / 328 | 98% | 45.11 | 175 / 178 |
| esophagus | 100% | 2585.26 | 1439 / 1445 | 98% | 49.50 | 180 / 183 |
| uterus | 99% | 1787.51 | 169 / 170 | 98% | 59.86 | 451 / 459 |
| lung | 99% | 2512.83 | 572 / 578 | 96% | 43.60 | 1113 / 1155 |
| liver | 100% | 3410.72 | 225 / 226 | 95% | 34.91 | 387 / 406 |
| bladder | 100% | 2750.10 | 21 / 21 | 94% | 44.70 | 476 / 504 |
| thymus | 100% | 2175.81 | 651 / 653 | 92% | 21.37 | 555 / 605 |
| stomach | 96% | 1434.41 | 344 / 359 | 93% | 22.45 | 267 / 286 |
| intestine | 100% | 2139.78 | 965 / 966 | 89% | 20.78 | 469 / 527 |
| kidney | 100% | 5322.67 | 89 / 89 | 89% | 21.44 | 799 / 901 |
| adrenal gland | 100% | 8502.61 | 258 / 258 | 88% | 27.21 | 203 / 230 |
| skin | 100% | 4522.15 | 1809 / 1809 | 81% | 13.76 | 381 / 472 |
| muscle | 100% | 2834.75 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 4444.58 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 56.72 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.71 | 1 / 1 |
| adipose | 99% | 1906.72 | 1197 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 92% | 1092.33 | 1228 / 1335 | 0% | 0 | 0 / 0 |
| heart | 90% | 1328.61 | 777 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 83% | 13.36 | 24 / 29 |
| eye | 0% | 0 | 0 / 0 | 74% | 12.36 | 59 / 80 |
| peripheral blood | 35% | 311.39 | 327 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0001525 | Biological process | angiogenesis |
| GO_0060716 | Biological process | labyrinthine layer blood vessel development |
| GO_0048666 | Biological process | neuron development |
| GO_0015015 | Biological process | heparan sulfate proteoglycan biosynthetic process, enzymatic modification |
| GO_0048286 | Biological process | lung alveolus development |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0017095 | Molecular function | heparan sulfate 6-O-sulfotransferase activity |
| GO_0008146 | Molecular function | sulfotransferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | HS6ST1 |
| Protein name | Heparan-sulfate 6-O-sulfotransferase 1 (HS6ST-1) (EC 2.8.2.-) |
| Synonyms | HS6ST |
| Description | FUNCTION: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid. . |
| Accessions | O60243 ENST00000259241.7 [O60243-1] |
