Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 14 studies | 44% ± 16% | |
| mast cell | 10 studies | 30% ± 14% | |
| GABAergic neuron | 8 studies | 42% ± 23% | |
| glutamatergic neuron | 8 studies | 48% ± 25% | |
| endothelial cell | 7 studies | 23% ± 8% | |
| microglial cell | 7 studies | 21% ± 4% | |
| oligodendrocyte precursor cell | 7 studies | 28% ± 6% | |
| macrophage | 6 studies | 24% ± 3% | |
| retinal cone cell | 5 studies | 36% ± 16% | |
| adipocyte | 5 studies | 20% ± 3% | |
| fibroblast | 5 studies | 23% ± 9% | |
| interneuron | 5 studies | 43% ± 19% | |
| epithelial cell | 4 studies | 31% ± 4% | |
| Mueller cell | 4 studies | 31% ± 10% | |
| amacrine cell | 4 studies | 27% ± 8% | |
| retina horizontal cell | 4 studies | 26% ± 10% | |
| retinal rod cell | 4 studies | 35% ± 6% | |
| GABAergic interneuron | 3 studies | 28% ± 7% | |
| GABAergic amacrine cell | 3 studies | 26% ± 7% | |
| hepatocyte | 3 studies | 33% ± 8% | |
| retinal pigment epithelial cell | 3 studies | 23% ± 3% | |
| monocyte | 3 studies | 16% ± 1% | |
| myeloid cell | 3 studies | 29% ± 11% | |
| neuron | 3 studies | 43% ± 14% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 2167.49 | 2641 / 2642 | 100% | 28.77 | 705 / 705 |
| esophagus | 100% | 1210.38 | 1444 / 1445 | 100% | 21.16 | 183 / 183 |
| ovary | 100% | 2154.06 | 180 / 180 | 100% | 15.23 | 429 / 430 |
| breast | 100% | 1824.86 | 459 / 459 | 100% | 19.94 | 1114 / 1118 |
| lung | 100% | 1807.08 | 576 / 578 | 100% | 20.30 | 1154 / 1155 |
| uterus | 100% | 1770.64 | 170 / 170 | 100% | 19.51 | 457 / 459 |
| prostate | 100% | 1443.51 | 245 / 245 | 99% | 25.19 | 499 / 502 |
| thymus | 100% | 1648.89 | 653 / 653 | 99% | 22.30 | 601 / 605 |
| bladder | 100% | 1765.38 | 21 / 21 | 99% | 20.20 | 499 / 504 |
| pancreas | 99% | 1106.62 | 326 / 328 | 99% | 20.24 | 177 / 178 |
| stomach | 100% | 1219.14 | 359 / 359 | 98% | 20.09 | 280 / 286 |
| intestine | 100% | 1501.32 | 966 / 966 | 98% | 18.82 | 515 / 527 |
| kidney | 100% | 1290.84 | 89 / 89 | 98% | 21.42 | 880 / 901 |
| liver | 100% | 1293.05 | 226 / 226 | 98% | 12.34 | 396 / 406 |
| adrenal gland | 100% | 5911.59 | 258 / 258 | 96% | 18.89 | 221 / 230 |
| skin | 100% | 2305.88 | 1808 / 1809 | 96% | 24.61 | 453 / 472 |
| adipose | 100% | 2184.83 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 19.47 | 29 / 29 |
| spleen | 100% | 1834.79 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 15.11 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 23.33 | 1 / 1 |
| blood vessel | 100% | 1338.34 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 96% | 730.74 | 768 / 803 | 0% | 0 | 0 / 0 |
| heart | 94% | 899.14 | 806 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 76% | 1726.82 | 704 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 73% | 7.21 | 58 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0010467 | Biological process | gene expression |
| GO_0015014 | Biological process | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process |
| GO_0030202 | Biological process | heparin metabolic process |
| GO_0015015 | Biological process | heparan sulfate proteoglycan biosynthetic process, enzymatic modification |
| GO_0060676 | Biological process | ureteric bud formation |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0004394 | Molecular function | heparan sulfate 2-O-sulfotransferase activity |
| Gene name | HS2ST1 |
| Protein name | Heparan sulfate 2-O-sulfotransferase 1 (2-O-sulfotransferase) (2OST) (EC 2.8.2.-) Heparan sulfate 2-O-sulfotransferase 1 |
| Synonyms | KIAA0448 HS2ST |
| Description | FUNCTION: Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues (By similarity). . |
| Accessions | Q7LGA3 ENST00000690674.1 ENST00000687893.1 ENST00000693745.1 A0A8I5KUP9 ENST00000370550.10 [Q7LGA3-1] ENST00000591456.1 ENST00000370551.8 [Q7LGA3-3] A0A8I5KW95 A0A8I5KR52 A0A8I5QKN0 K7EP71 ENST00000689904.1 |