Insufficient scRNA-seq data for expression of HRH4 at single-cell level.
Insufficient scRNA-seq data for expression of HRH4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 15.00 | 21 / 21 | 1% | 0.01 | 3 / 504 |
liver | 94% | 14.00 | 213 / 226 | 0% | 0 | 0 / 406 |
spleen | 94% | 22.31 | 227 / 241 | 0% | 0 | 0 / 0 |
lung | 93% | 19.71 | 536 / 578 | 1% | 0.02 | 13 / 1155 |
adipose | 90% | 14.37 | 1084 / 1204 | 0% | 0 | 0 / 0 |
uterus | 89% | 11.51 | 152 / 170 | 0% | 0 | 0 / 459 |
prostate | 89% | 10.15 | 219 / 245 | 0% | 0 | 0 / 502 |
breast | 88% | 10.28 | 404 / 459 | 0% | 0.00 | 3 / 1118 |
adrenal gland | 88% | 10.31 | 226 / 258 | 0% | 0.00 | 1 / 230 |
blood vessel | 87% | 9.67 | 1162 / 1335 | 0% | 0 | 0 / 0 |
esophagus | 85% | 12.04 | 1231 / 1445 | 0% | 0 | 0 / 183 |
intestine | 84% | 10.60 | 813 / 966 | 1% | 0.02 | 5 / 527 |
skin | 81% | 9.41 | 1464 / 1809 | 0% | 0.00 | 1 / 472 |
muscle | 80% | 7.75 | 642 / 803 | 0% | 0 | 0 / 0 |
thymus | 74% | 6.76 | 486 / 653 | 0% | 0.00 | 2 / 605 |
ovary | 74% | 10.16 | 133 / 180 | 0% | 0 | 0 / 430 |
peripheral blood | 70% | 58.40 | 649 / 929 | 0% | 0 | 0 / 0 |
stomach | 63% | 5.68 | 225 / 359 | 1% | 0.01 | 2 / 286 |
kidney | 62% | 5.49 | 55 / 89 | 0% | 0.00 | 2 / 901 |
heart | 60% | 4.27 | 518 / 861 | 0% | 0 | 0 / 0 |
brain | 55% | 3.96 | 1464 / 2642 | 0% | 0 | 0 / 705 |
pancreas | 44% | 3.16 | 143 / 328 | 2% | 0.05 | 4 / 178 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007197 | Biological process | adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway |
GO_0043408 | Biological process | regulation of MAPK cascade |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0006954 | Biological process | inflammatory response |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_0098664 | Biological process | G protein-coupled serotonin receptor signaling pathway |
GO_0008150 | Biological process | biological_process |
GO_0007187 | Biological process | G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger |
GO_0030425 | Cellular component | dendrite |
GO_0045202 | Cellular component | synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0004993 | Molecular function | G protein-coupled serotonin receptor activity |
GO_0016907 | Molecular function | G protein-coupled acetylcholine receptor activity |
GO_0004969 | Molecular function | histamine receptor activity |
Gene name | HRH4 |
Protein name | Histamine H4 receptor (H4R) (HH4R) (AXOR35) (G-protein coupled receptor 105) (GPRv53) (Pfi-013) (SP9144) |
Synonyms | GPCR105 |
Description | FUNCTION: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). . |
Accessions | ENST00000256906.5 [Q9H3N8-1] ENST00000426880.2 [Q9H3N8-2] Q9H3N8 |