HRH4 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HRH4 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HRH4 at tissue level.

III. Associated gene sets

GO_0007197Biological processadenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway
GO_0043408Biological processregulation of MAPK cascade
GO_0007204Biological processpositive regulation of cytosolic calcium ion concentration
GO_0006954Biological processinflammatory response
GO_0007268Biological processchemical synaptic transmission
GO_0098664Biological processG protein-coupled serotonin receptor signaling pathway
GO_0008150Biological processbiological_process
GO_0007187Biological processG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO_0030425Cellular componentdendrite
GO_0045202Cellular componentsynapse
GO_0005886Cellular componentplasma membrane
GO_0004993Molecular functionG protein-coupled serotonin receptor activity
GO_0016907Molecular functionG protein-coupled acetylcholine receptor activity
GO_0004969Molecular functionhistamine receptor activity

IV. Literature review

[source]
Gene nameHRH4
Protein nameHistamine H4 receptor (H4R) (HH4R) (AXOR35) (G-protein coupled receptor 105) (GPRv53) (Pfi-013) (SP9144)
SynonymsGPCR105
DescriptionFUNCTION: The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues. Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist). .

AccessionsENST00000256906.5 [Q9H3N8-1]
ENST00000426880.2 [Q9H3N8-2]
Q9H3N8