HOXB8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HOXB8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HOXB8 at tissue level.

III. Associated gene sets

GO_0019233Biological processsensory perception of pain
GO_0008344Biological processadult locomotory behavior
GO_0021516Biological processdorsal spinal cord development
GO_0048704Biological processembryonic skeletal system morphogenesis
GO_0045638Biological processnegative regulation of myeloid cell differentiation
GO_0007625Biological processgrooming behavior
GO_0009952Biological processanterior/posterior pattern specification
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameHOXB8
Protein nameHomeobox protein Hox-B8 (Homeobox protein Hox-2.4) (Homeobox protein Hox-2D)
Homeobox B8
SynonymsHOX2D
hCG_1639847
DescriptionFUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

FUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. .

FUNCTION: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. .

AccessionsENST00000239144.5
ENST00000576562.1
ENST00000498634.2
I3L3R1
I3L383
P17481