Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 6 studies | 39% ± 16% | |
basal cell | 6 studies | 26% ± 8% | |
retinal cone cell | 5 studies | 38% ± 13% | |
retinal rod cell | 5 studies | 22% ± 5% | |
Mueller cell | 5 studies | 34% ± 15% | |
retinal bipolar neuron | 4 studies | 29% ± 7% | |
ciliated cell | 4 studies | 28% ± 9% | |
GABAergic neuron | 4 studies | 43% ± 15% | |
amacrine cell | 3 studies | 23% ± 8% | |
retina horizontal cell | 3 studies | 29% ± 10% | |
ON-bipolar cell | 3 studies | 35% ± 14% | |
rod bipolar cell | 3 studies | 30% ± 9% | |
glutamatergic neuron | 3 studies | 62% ± 2% | |
goblet cell | 3 studies | 20% ± 4% | |
interneuron | 3 studies | 45% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 2233.06 | 89 / 89 | 96% | 35.52 | 866 / 901 |
thymus | 100% | 2026.76 | 652 / 653 | 92% | 20.98 | 557 / 605 |
prostate | 91% | 1017.36 | 223 / 245 | 98% | 19.73 | 492 / 502 |
liver | 100% | 2776.06 | 226 / 226 | 88% | 15.25 | 357 / 406 |
pancreas | 100% | 2952.66 | 328 / 328 | 88% | 12.13 | 156 / 178 |
stomach | 75% | 1569.01 | 269 / 359 | 92% | 23.90 | 264 / 286 |
lung | 66% | 604.91 | 384 / 578 | 95% | 20.51 | 1092 / 1155 |
breast | 57% | 750.29 | 261 / 459 | 98% | 28.53 | 1093 / 1118 |
intestine | 47% | 1173.82 | 456 / 966 | 95% | 24.85 | 501 / 527 |
esophagus | 40% | 1355.28 | 575 / 1445 | 96% | 27.21 | 175 / 183 |
adrenal gland | 98% | 1275.53 | 253 / 258 | 35% | 2.88 | 81 / 230 |
bladder | 33% | 276.52 | 7 / 21 | 85% | 15.50 | 430 / 504 |
skin | 72% | 2263.00 | 1304 / 1809 | 33% | 4.00 | 155 / 472 |
ovary | 9% | 43.79 | 17 / 180 | 94% | 12.37 | 403 / 430 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.64 | 1 / 1 |
uterus | 11% | 117.65 | 18 / 170 | 88% | 20.57 | 405 / 459 |
tonsil | 0% | 0 | 0 / 0 | 93% | 22.15 | 42 / 45 |
brain | 76% | 1125.89 | 2005 / 2642 | 7% | 0.58 | 49 / 705 |
heart | 48% | 286.44 | 416 / 861 | 0% | 0 | 0 / 0 |
spleen | 37% | 171.05 | 88 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 26% | 2.82 | 21 / 80 |
lymph node | 0% | 0 | 0 / 0 | 21% | 1.47 | 6 / 29 |
peripheral blood | 18% | 367.45 | 163 / 929 | 0% | 0 | 0 / 0 |
adipose | 17% | 102.24 | 199 / 1204 | 0% | 0 | 0 / 0 |
muscle | 1% | 3.42 | 5 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 2.52 | 5 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007040 | Biological process | lysosome organization |
GO_0031122 | Biological process | cytoplasmic microtubule organization |
GO_1905719 | Biological process | protein localization to perinuclear region of cytoplasm |
GO_1905198 | Biological process | manchette assembly |
GO_0007030 | Biological process | Golgi organization |
GO_0008333 | Biological process | endosome to lysosome transport |
GO_0007032 | Biological process | endosome organization |
GO_0015031 | Biological process | protein transport |
GO_0045022 | Biological process | early endosome to late endosome transport |
GO_0030705 | Biological process | cytoskeleton-dependent intracellular transport |
GO_0030897 | Cellular component | HOPS complex |
GO_0005874 | Cellular component | microtubule |
GO_0005813 | Cellular component | centrosome |
GO_0070695 | Cellular component | FHF complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0042803 | Molecular function | protein homodimerization activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0051959 | Molecular function | dynein light intermediate chain binding |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
Gene name | HOOK1 |
Protein name | Hook homolog 1 (Drosophila), isoform CRA_b (Hook microtubule tethering protein 1) HOOK1 protein Hook microtubule tethering protein 1 Protein Hook homolog 1 (h-hook1) (hHK1) Hook Microtubule-Tethering Protein 1 |
Synonyms | hCG_23216 |
Description | FUNCTION: Component of the FTS/Hook/FHIP complex (FHF complex) . The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) . FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell . Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). . |
Accessions | Q32Q39 ENST00000455990.5 A0A8I5KQJ5 ENST00000685567.1 ENST00000371208.5 [Q9UJC3-1] A0A8I5KRQ9 ENST00000687049.1 ENST00000686522.1 B1AK95 A0A8I5KRT5 Q9UJC3 A0A2H4PWH9 |