HOOK1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007040Biological processlysosome organization
GO_0031122Biological processcytoplasmic microtubule organization
GO_1905719Biological processprotein localization to perinuclear region of cytoplasm
GO_1905198Biological processmanchette assembly
GO_0007030Biological processGolgi organization
GO_0008333Biological processendosome to lysosome transport
GO_0007032Biological processendosome organization
GO_0015031Biological processprotein transport
GO_0045022Biological processearly endosome to late endosome transport
GO_0030705Biological processcytoskeleton-dependent intracellular transport
GO_0030897Cellular componentHOPS complex
GO_0005874Cellular componentmicrotubule
GO_0005813Cellular componentcentrosome
GO_0070695Cellular componentFHF complex
GO_0005737Cellular componentcytoplasm
GO_0042803Molecular functionprotein homodimerization activity
GO_0042802Molecular functionidentical protein binding
GO_0008017Molecular functionmicrotubule binding
GO_0051959Molecular functiondynein light intermediate chain binding
GO_0005515Molecular functionprotein binding
GO_0003779Molecular functionactin binding

IV. Literature review

[source]
Gene nameHOOK1
Protein nameHook homolog 1 (Drosophila), isoform CRA_b (Hook microtubule tethering protein 1)
HOOK1 protein
Hook microtubule tethering protein 1
Protein Hook homolog 1 (h-hook1) (hHK1)
Hook Microtubule-Tethering Protein 1
SynonymshCG_23216
DescriptionFUNCTION: Component of the FTS/Hook/FHIP complex (FHF complex) . The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) . FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell . Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton (By similarity). .

AccessionsQ32Q39
ENST00000455990.5
A0A8I5KQJ5
ENST00000685567.1
ENST00000371208.5 [Q9UJC3-1]
A0A8I5KRQ9
ENST00000687049.1
ENST00000686522.1
B1AK95
A0A8I5KRT5
Q9UJC3
A0A2H4PWH9