HES3 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of HES3 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of HES3 at tissue level.

III. Associated gene sets

GO_0050767Biological processregulation of neurogenesis
GO_0009952Biological processanterior/posterior pattern specification
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0046983Molecular functionprotein dimerization activity
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameHES3
Protein nameTranscription factor HES-3 (Class B basic helix-loop-helix protein 43) (bHLHb43) (Hairy and enhancer of split 3)
Hes family bHLH transcription factor 3
SynonymsBHLHB43
DescriptionFUNCTION: Transcriptional repressor of genes that require a bHLH protein for their transcription. .

AccessionsA0A9L9PX90
ENST00000377898.4
Q5TGS1
ENST00000706530.1