Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| microglial cell | 11 studies | 34% ± 14% | |
| oligodendrocyte | 9 studies | 36% ± 12% | |
| endothelial cell | 8 studies | 29% ± 13% | |
| GABAergic neuron | 7 studies | 45% ± 28% | |
| glutamatergic neuron | 7 studies | 48% ± 28% | |
| oligodendrocyte precursor cell | 7 studies | 28% ± 12% | |
| retinal cone cell | 7 studies | 42% ± 19% | |
| interneuron | 6 studies | 42% ± 28% | |
| astrocyte | 6 studies | 40% ± 18% | |
| neuron | 4 studies | 30% ± 16% | |
| retinal rod cell | 4 studies | 40% ± 18% | |
| dendritic cell | 4 studies | 18% ± 2% | |
| macrophage | 4 studies | 34% ± 9% | |
| monocyte | 4 studies | 23% ± 7% | |
| mast cell | 4 studies | 21% ± 4% | |
| GABAergic interneuron | 3 studies | 25% ± 2% | |
| epithelial cell | 3 studies | 17% ± 1% | |
| cardiac muscle cell | 3 studies | 24% ± 6% | |
| amacrine cell | 3 studies | 27% ± 14% | |
| alveolar macrophage | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 2538.51 | 244 / 245 | 3% | 0.06 | 17 / 502 |
| bladder | 100% | 2499.67 | 21 / 21 | 3% | 0.08 | 14 / 504 |
| lung | 100% | 3209.86 | 578 / 578 | 2% | 0.06 | 22 / 1155 |
| esophagus | 100% | 3018.02 | 1445 / 1445 | 1% | 0.03 | 2 / 183 |
| breast | 100% | 2408.78 | 459 / 459 | 1% | 0.03 | 11 / 1118 |
| kidney | 100% | 1986.45 | 89 / 89 | 1% | 0.04 | 8 / 901 |
| stomach | 100% | 2113.19 | 359 / 359 | 1% | 0.03 | 2 / 286 |
| intestine | 100% | 2523.97 | 966 / 966 | 1% | 0.01 | 3 / 527 |
| adrenal gland | 100% | 2298.79 | 258 / 258 | 0% | 0.01 | 1 / 230 |
| uterus | 100% | 2723.41 | 170 / 170 | 0% | 0.01 | 1 / 459 |
| adipose | 100% | 2451.73 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| ovary | 100% | 2263.99 | 180 / 180 | 0% | 0 | 0 / 430 |
| skin | 100% | 3681.53 | 1809 / 1809 | 0% | 0 | 0 / 472 |
| spleen | 100% | 2626.61 | 241 / 241 | 0% | 0 | 0 / 0 |
| thymus | 100% | 2477.99 | 653 / 653 | 0% | 0 | 0 / 605 |
| blood vessel | 100% | 2744.32 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 2229.91 | 802 / 803 | 0% | 0 | 0 / 0 |
| brain | 98% | 2977.74 | 2592 / 2642 | 1% | 0.01 | 4 / 705 |
| peripheral blood | 98% | 2343.95 | 908 / 929 | 0% | 0 | 0 / 0 |
| heart | 96% | 2438.08 | 825 / 861 | 0% | 0 | 0 / 0 |
| pancreas | 93% | 819.61 | 304 / 328 | 2% | 0.04 | 3 / 178 |
| liver | 93% | 788.45 | 210 / 226 | 0% | 0 | 0 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006511 | Biological process | ubiquitin-dependent protein catabolic process |
| GO_0016567 | Biological process | protein ubiquitination |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0061630 | Molecular function | ubiquitin protein ligase activity |
| Gene name | HERC3 |
| Protein name | Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3) Uncharacterized protein HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| Synonyms | KIAA0032 |
| Description | FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. . |
| Accessions | H0Y8G9 Q15034 C9J6Z1 ENST00000407637.5 [Q15034-2] ENST00000452979.5 ENST00000422770.5 Q4W5H5 C9J8E7 C9JFL2 ENST00000426683.5 ENST00000402738.6 [Q15034-1] ENST00000512194.2 ENST00000431413.5 ENST00000264345.7 [Q15034-1] C9JKA7 |