Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| endothelial cell | 5 studies | 22% ± 7% | |
| epithelial cell | 4 studies | 21% ± 4% | |
| microglial cell | 3 studies | 19% ± 2% | |
| GABAergic neuron | 3 studies | 43% ± 2% | |
| glutamatergic neuron | 3 studies | 55% ± 4% | |
| oligodendrocyte precursor cell | 3 studies | 24% ± 5% | |
| astrocyte | 3 studies | 22% ± 3% | |
| oligodendrocyte | 3 studies | 22% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2009.81 | 1444 / 1445 | 100% | 33.55 | 183 / 183 |
| lung | 100% | 1834.71 | 576 / 578 | 99% | 20.38 | 1142 / 1155 |
| intestine | 100% | 1960.42 | 966 / 966 | 98% | 18.89 | 519 / 527 |
| stomach | 100% | 1652.86 | 359 / 359 | 98% | 22.12 | 281 / 286 |
| breast | 100% | 2587.61 | 459 / 459 | 98% | 26.35 | 1091 / 1118 |
| ovary | 100% | 2439.09 | 180 / 180 | 97% | 15.89 | 419 / 430 |
| skin | 100% | 3756.40 | 1809 / 1809 | 97% | 29.43 | 458 / 472 |
| bladder | 100% | 2287.24 | 21 / 21 | 95% | 15.92 | 479 / 504 |
| pancreas | 100% | 1749.80 | 327 / 328 | 95% | 12.99 | 169 / 178 |
| uterus | 100% | 2531.78 | 170 / 170 | 93% | 15.88 | 426 / 459 |
| thymus | 100% | 2076.38 | 653 / 653 | 88% | 9.83 | 534 / 605 |
| prostate | 100% | 1852.84 | 245 / 245 | 86% | 10.41 | 433 / 502 |
| kidney | 100% | 1197.90 | 89 / 89 | 86% | 10.43 | 771 / 901 |
| brain | 85% | 636.69 | 2234 / 2642 | 94% | 10.78 | 664 / 705 |
| adrenal gland | 100% | 1803.21 | 258 / 258 | 69% | 5.52 | 158 / 230 |
| liver | 96% | 863.82 | 216 / 226 | 71% | 7.73 | 289 / 406 |
| adipose | 100% | 2608.52 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1763.50 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2235.27 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 4.34 | 1 / 1 |
| muscle | 98% | 1332.85 | 790 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 16.24 | 42 / 45 |
| heart | 93% | 994.15 | 800 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 90% | 11.09 | 72 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 76% | 17.84 | 22 / 29 |
| peripheral blood | 56% | 1867.84 | 519 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_2000234 | Biological process | positive regulation of rRNA processing |
| GO_0000462 | Biological process | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| GO_0045943 | Biological process | positive regulation of transcription by RNA polymerase I |
| GO_0042274 | Biological process | ribosomal small subunit biogenesis |
| GO_0005730 | Cellular component | nucleolus |
| GO_0001650 | Cellular component | fibrillar center |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0034455 | Cellular component | t-UTP complex |
| GO_0030686 | Cellular component | 90S preribosome |
| GO_0016020 | Cellular component | membrane |
| GO_0032040 | Cellular component | small-subunit processome |
| GO_0030515 | Molecular function | snoRNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | HEATR1 |
| Protein name | HEAT repeat-containing protein 1 (Protein BAP28) (U3 small nucleolar RNA-associated protein 10 homolog) [Cleaved into: HEAT repeat-containing protein 1, N-terminally processed] HEAT repeat-containing protein 1 |
| Synonyms | UTP10 BAP28 |
| Description | FUNCTION: Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I . Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome . . FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA. . FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA. . FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA. . FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA. . FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA. . |
| Accessions | ENST00000366581.6 Q96ES5 ENST00000366579.1 A2VDI1 Q9H583 B2RWN5 ENST00000366582.8 Q5T3Q7 Q6P664 |
