Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 12 studies | 20% ± 3% | |
classical monocyte | 10 studies | 25% ± 14% | |
monocyte | 6 studies | 25% ± 9% | |
fibroblast | 6 studies | 18% ± 2% | |
macrophage | 5 studies | 22% ± 2% | |
epithelial cell | 5 studies | 38% ± 24% | |
basal cell | 5 studies | 22% ± 5% | |
B cell | 4 studies | 30% ± 8% | |
dendritic cell | 4 studies | 49% ± 26% | |
natural killer cell | 4 studies | 21% ± 5% | |
squamous epithelial cell | 4 studies | 37% ± 22% | |
hematopoietic precursor cell | 4 studies | 22% ± 11% | |
CD8-positive, alpha-beta T cell | 3 studies | 24% ± 4% | |
conventional dendritic cell | 3 studies | 30% ± 18% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 23% ± 3% | |
non-classical monocyte | 3 studies | 40% ± 15% | |
glutamatergic neuron | 3 studies | 32% ± 12% | |
myeloid cell | 3 studies | 35% ± 14% | |
ciliated cell | 3 studies | 31% ± 17% | |
pericyte | 3 studies | 16% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 3416.22 | 459 / 459 | 100% | 18.67 | 1118 / 1118 |
esophagus | 100% | 3519.49 | 1445 / 1445 | 100% | 16.96 | 183 / 183 |
intestine | 100% | 3305.95 | 966 / 966 | 100% | 10.67 | 527 / 527 |
ovary | 100% | 2777.18 | 180 / 180 | 100% | 8.62 | 430 / 430 |
stomach | 100% | 2476.86 | 359 / 359 | 100% | 11.42 | 286 / 286 |
lung | 100% | 3819.58 | 577 / 578 | 100% | 13.16 | 1155 / 1155 |
prostate | 100% | 2955.78 | 245 / 245 | 100% | 12.28 | 501 / 502 |
uterus | 100% | 3132.46 | 170 / 170 | 100% | 12.26 | 458 / 459 |
liver | 100% | 1853.57 | 226 / 226 | 100% | 6.80 | 405 / 406 |
pancreas | 100% | 1553.05 | 327 / 328 | 100% | 11.66 | 178 / 178 |
thymus | 100% | 3245.03 | 653 / 653 | 100% | 11.85 | 603 / 605 |
bladder | 100% | 3382.33 | 21 / 21 | 100% | 11.39 | 502 / 504 |
kidney | 100% | 2471.71 | 89 / 89 | 99% | 11.43 | 893 / 901 |
brain | 99% | 1854.76 | 2609 / 2642 | 100% | 11.46 | 705 / 705 |
skin | 100% | 4081.48 | 1809 / 1809 | 98% | 11.19 | 464 / 472 |
adrenal gland | 100% | 2655.20 | 258 / 258 | 98% | 11.12 | 226 / 230 |
adipose | 100% | 3848.14 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 4621.65 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 10.24 | 29 / 29 |
muscle | 100% | 3760.87 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3390.64 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 12.40 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.83 | 1 / 1 |
peripheral blood | 99% | 5396.60 | 918 / 929 | 0% | 0 | 0 / 0 |
heart | 98% | 2484.40 | 843 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 94% | 5.78 | 75 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0080135 | Biological process | regulation of cellular response to stress |
GO_1901797 | Biological process | negative regulation of signal transduction by p53 class mediator |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0031625 | Molecular function | ubiquitin protein ligase binding |
GO_0005515 | Molecular function | protein binding |
Gene name | HAPSTR1 |
Protein name | HUWE1 associated protein modifying stress responses HUWE1-associated protein modifying stress responses 1 (Telomere attrition and p53 response 1 protein) |
Synonyms | C16orf72 TAPR1 |
Description | FUNCTION: Acts as a central player within a network of stress response pathways promoting cellular adaptability. The E3 ligase HUWE1 assists HAPSTR1 in controlling stress signaling and in turn, HUWE1 feeds back to promote the degradation of HAPSTR1. HAPSTR1 represents a central coordination mechanism for stress response programs . Functions as a negative regulator of TP53/P53 in the cellular response to telomere erosion and probably also DNA damage . May attenuate p53/TP53 activation through the E3 ubiquitin ligase HUWE1 . . |
Accessions | ENST00000574285.2 ENST00000327827.12 [Q14CZ0-1] Q14CZ0 A0A087X1J2 |