H4C7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H4C7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H4C7 at tissue level.

III. Associated gene sets

GO_0008150Biological processbiological_process
GO_0006334Biological processnucleosome assembly
GO_0000786Cellular componentnucleosome
GO_0005634Cellular componentnucleus
GO_0030527Molecular functionstructural constituent of chromatin
GO_0046982Molecular functionprotein heterodimerization activity
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameH4C7
Protein nameHistone H4-like protein type G (H4-clustered histone 7)
SynonymsHIST1H4G
H4/L
H4FL
DescriptionFUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). .

AccessionsENST00000611444.2
Q99525