H3C1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H3C1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H3C1 at tissue level.

III. Associated gene sets

GO_0006325Biological processchromatin organization
GO_0032200Biological processtelomere organization
GO_0010467Biological processgene expression
GO_0040029Biological processepigenetic regulation of gene expression
GO_0006334Biological processnucleosome assembly
GO_0070062Cellular componentextracellular exosome
GO_0032991Cellular componentprotein-containing complex
GO_0005654Cellular componentnucleoplasm
GO_0005576Cellular componentextracellular region
GO_0000786Cellular componentnucleosome
GO_0016020Cellular componentmembrane
GO_0005634Cellular componentnucleus
GO_0030527Molecular functionstructural constituent of chromatin
GO_0046982Molecular functionprotein heterodimerization activity
GO_0003677Molecular functionDNA binding
GO_0045296Molecular functioncadherin binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameH3C1
Protein nameHistone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
SynonymsH3C6
HIST1H3I;
H3C11
H3C12
H3FD
HIST1H3J
H3FI
HIST1H3H;
HIST1H3A;
H3FH
HIST1H3C;
HIST1H3B;
H3FJ
H3FK
HIST1H3G;
HIST1H3E;
H3C10
H3C3
H3FC
H3C7
HIST1H3F;
H3FL
H3C8
H3C2
H3C4
HIST1H3D;
H3FF
H3FB
H3FA
DescriptionFUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

AccessionsENST00000612966.3
ENST00000618052.2
ENST00000614911.3
P68431
ENST00000369163.4
ENST00000621411.3
ENST00000614378.2
ENST00000634733.1
ENST00000359303.4
ENST00000613854.2
ENST00000685041.1
ENST00000356476.3
ENST00000616365.2