H2BC12 | OmnibusX

Name	Number of supported studies	Average coverage
plasmacytoid dendritic cell	5 studies	20% ± 5%	Explore
pro-B cell	4 studies	30% ± 15%	Explore
B cell	4 studies	25% ± 13%	Explore
precursor B cell	3 studies	33% ± 11%	Explore
epithelial cell	3 studies	33% ± 24%	Explore
platelet	3 studies	31% ± 12%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of H2BC12 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	875.49	245 / 245	99%	377.12	499 / 502
ovary	99%	363.19	179 / 180	98%	340.40	422 / 430
breast	100%	436.73	459 / 459	95%	252.97	1062 / 1118
thymus	100%	524.55	652 / 653	95%	139.31	574 / 605
esophagus	100%	465.64	1441 / 1445	93%	184.58	171 / 183
lung	100%	624.53	578 / 578	92%	191.59	1057 / 1155
liver	100%	694.48	225 / 226	91%	203.07	369 / 406
uterus	100%	473.05	170 / 170	90%	232.90	415 / 459
skin	100%	436.24	1805 / 1809	90%	213.78	425 / 472
pancreas	99%	378.78	326 / 328	86%	132.90	153 / 178
stomach	99%	336.35	355 / 359	83%	135.03	238 / 286
bladder	100%	352.67	21 / 21	81%	159.84	410 / 504
intestine	100%	449.10	966 / 966	81%	122.37	425 / 527
adrenal gland	98%	372.42	253 / 258	64%	78.23	148 / 230
kidney	88%	206.27	78 / 89	55%	56.76	493 / 901
peripheral blood	100%	2181.60	929 / 929	0%	0	0 / 0
spleen	100%	869.90	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	129.09	1 / 1
blood vessel	100%	465.16	1332 / 1335	0%	0	0 / 0
adipose	100%	467.54	1201 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	96%	204.27	43 / 45
eye	0%	0	0 / 0	95%	276.55	76 / 80
lymph node	0%	0	0 / 0	93%	228.48	27 / 29
heart	91%	229.90	782 / 861	0%	0	0 / 0
brain	47%	85.40	1229 / 2642	27%	25.54	193 / 705
muscle	21%	29.48	168 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0050829	Biological process	defense response to Gram-negative bacterium
GO_0061844	Biological process	antimicrobial humoral immune response mediated by antimicrobial peptide
GO_0031640	Biological process	killing of cells of another organism
GO_0002227	Biological process	innate immune response in mucosa
GO_0050830	Biological process	defense response to Gram-positive bacterium
GO_0019731	Biological process	antibacterial humoral response
GO_0005615	Cellular component	extracellular space
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0000786	Cellular component	nucleosome
GO_0005634	Cellular component	nucleus
GO_0046982	Molecular function	protein heterodimerization activity
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding
GO_0030527	Molecular function	structural constituent of chromatin
GO_0003674	Molecular function	molecular_function

Gene name	H2BC12
Protein name	Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Synonyms	HIST1H2BK H2BFT HIRIP1
Description	FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; FUNCTION: Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Accessions	O60814 ENST00000356950.2

H2BC12 report