H1-7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H1-7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H1-7 at tissue level.

III. Associated gene sets

GO_0007290Biological processspermatid nucleus elongation
GO_0035092Biological processsperm DNA condensation
GO_0045910Biological processnegative regulation of DNA recombination
GO_0030261Biological processchromosome condensation
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003690Molecular functiondouble-stranded DNA binding
GO_0031492Molecular functionnucleosomal DNA binding
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameH1-7
Protein nameTestis-specific H1 histone (Haploid germ cell-specific nuclear protein 1) (Histone H1.7) (Histone H1t2)
SynonymsH1FNT
HANP1
DescriptionFUNCTION: Essential for normal spermatogenesis and male fertility . Required for proper cell restructuring and DNA condensation during the elongation phase of spermiogenesis. Involved in the histone-protamine transition of sperm chromatin and the subsequent production of functional sperm. Binds both double-stranded and single-stranded DNA, ATP and protamine-1. .

AccessionsENST00000335017.1
Q75WM6