H1-1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H1-1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H1-1 at tissue level.

III. Associated gene sets

GO_0048260Biological processpositive regulation of receptor-mediated endocytosis
GO_0007283Biological processspermatogenesis
GO_0045910Biological processnegative regulation of DNA recombination
GO_0006334Biological processnucleosome assembly
GO_0030261Biological processchromosome condensation
GO_0009986Cellular componentcell surface
GO_0000791Cellular componenteuchromatin
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0031982Cellular componentvesicle
GO_0000786Cellular componentnucleosome
GO_0005634Cellular componentnucleus
GO_0003690Molecular functiondouble-stranded DNA binding
GO_0030527Molecular functionstructural constituent of chromatin
GO_0031490Molecular functionchromatin DNA binding
GO_0008201Molecular functionheparin binding
GO_0031492Molecular functionnucleosomal DNA binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameH1-1
Protein nameHistone H1.1 (Histone H1a)
SynonymsHIST1H1A
H1F1
DescriptionFUNCTION: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity). .

AccessionsENST00000244573.5
Q02539