GUCA1C | OmnibusX

Name	Number of supported studies	Average coverage
retinal cone cell	8 studies	74% ± 21%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of GUCA1C at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	851.52	328 / 328	19%	1.35	33 / 178
stomach	54%	61.47	193 / 359	3%	0.04	8 / 286
heart	38%	80.34	331 / 861	0%	0	0 / 0
bladder	33%	188.71	7 / 21	1%	0.02	4 / 504
kidney	4%	2.04	4 / 89	5%	0.14	41 / 901
ovary	8%	12.71	14 / 180	1%	0.06	3 / 430
eye	0%	0	0 / 0	6%	1.36	5 / 80
brain	5%	3.51	129 / 2642	1%	0.07	9 / 705
adrenal gland	0%	0.17	1 / 258	2%	0.10	5 / 230
esophagus	0%	0	0 / 1445	2%	0.04	4 / 183
intestine	0%	0	0 / 966	2%	0.07	8 / 527
lung	0%	0.08	1 / 578	1%	0.07	11 / 1155
uterus	0%	0	0 / 170	1%	0.06	5 / 459
blood vessel	1%	0.52	7 / 1335	0%	0	0 / 0
skin	0%	0.05	1 / 1809	0%	0.01	2 / 472
prostate	0%	0.44	1 / 245	0%	0	0 / 502
breast	0%	0	0 / 459	0%	0.00	3 / 1118
liver	0%	0	0 / 226	0%	1.32	1 / 406
adipose	0%	0.08	2 / 1204	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
thymus	0%	0	0 / 653	0%	0	0 / 605
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007165	Biological process	signal transduction
GO_0007601	Biological process	visual perception
GO_0097381	Cellular component	photoreceptor disc membrane
GO_0005509	Molecular function	calcium ion binding
GO_0008048	Molecular function	calcium sensitive guanylate cyclase activator activity
GO_0005515	Molecular function	protein binding

Gene name	GUCA1C
Protein name	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C) Guanylate cyclase activator 1C (Guanylyl cyclase-activating protein 3) Guanylate cyclase activator 1C
Synonyms	hCG_26941 GCAP3
Description	FUNCTION: Stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
Accessions	ENST00000393963.7 O95843 C9JNI2 ENST00000471108.1 C9J7M7 ENST00000261047.8 [O95843-1] Q3SY23

GUCA1C report