GTF3C4 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GTF3C4 at tissue level.

III. Associated gene sets

GO_0006384Biological processtranscription initiation at RNA polymerase III promoter
GO_0042797Biological processtRNA transcription by RNA polymerase III
GO_0042791Biological process5S class rRNA transcription by RNA polymerase III
GO_0006338Biological processchromatin remodeling
GO_0006383Biological processtranscription by RNA polymerase III
GO_0000127Cellular componenttranscription factor TFIIIC complex
GO_0005654Cellular componentnucleoplasm
GO_0005739Cellular componentmitochondrion
GO_0003677Molecular functionDNA binding
GO_0008047Molecular functionenzyme activator activity
GO_0004402Molecular functionhistone acetyltransferase activity
GO_0000995Molecular functionRNA polymerase III general transcription initiation factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGTF3C4
Protein nameGeneral transcription factor IIIC subunit 4
GTF3C4 protein
General transcription factor 3C polypeptide 4 (EC 2.3.1.48) (TF3C-delta) (Transcription factor IIIC 90 kDa subunit) (TFIIIC 90 kDa subunit) (TFIIIC90) (Transcription factor IIIC subunit delta)
Synonyms
DescriptionFUNCTION: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.

AccessionsENST00000483873.6
Q9UKN8
Q05CN7
F2Z356
ENST00000372146.5