Insufficient scRNA-seq data for expression of GSX2 at single-cell level.
Insufficient scRNA-seq data for expression of GSX2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 81% | 25.65 | 2142 / 2642 | 37% | 3.70 | 262 / 705 |
skin | 55% | 15.39 | 992 / 1809 | 0% | 0.00 | 1 / 472 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.20 | 3 / 29 |
thymus | 1% | 0.10 | 5 / 653 | 9% | 0.24 | 54 / 605 |
peripheral blood | 10% | 6.93 | 89 / 929 | 0% | 0 | 0 / 0 |
bladder | 5% | 0.29 | 1 / 21 | 1% | 0.04 | 5 / 504 |
heart | 6% | 0.50 | 49 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 5% | 0.48 | 72 / 1335 | 0% | 0 | 0 / 0 |
stomach | 4% | 0.40 | 16 / 359 | 0% | 0.00 | 1 / 286 |
kidney | 3% | 0.34 | 3 / 89 | 1% | 0.02 | 10 / 901 |
spleen | 4% | 0.32 | 10 / 241 | 0% | 0 | 0 / 0 |
uterus | 2% | 0.15 | 3 / 170 | 2% | 0.03 | 8 / 459 |
intestine | 3% | 0.27 | 31 / 966 | 0% | 0.02 | 1 / 527 |
breast | 3% | 0.23 | 14 / 459 | 0% | 0.00 | 2 / 1118 |
liver | 3% | 0.17 | 6 / 226 | 0% | 0.00 | 1 / 406 |
tonsil | 0% | 0 | 0 / 0 | 2% | 0.09 | 1 / 45 |
esophagus | 1% | 0.08 | 11 / 1445 | 1% | 0.02 | 2 / 183 |
adipose | 2% | 0.16 | 22 / 1204 | 0% | 0 | 0 / 0 |
lung | 0% | 0.01 | 1 / 578 | 1% | 0.02 | 12 / 1155 |
pancreas | 0% | 0 | 0 / 328 | 1% | 0.03 | 2 / 178 |
ovary | 1% | 0.04 | 1 / 180 | 0% | 0.01 | 1 / 430 |
adrenal gland | 1% | 0.06 | 2 / 258 | 0% | 0 | 0 / 230 |
prostate | 0% | 0.02 | 1 / 245 | 0% | 0 | 0 / 502 |
muscle | 0% | 0.02 | 2 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0002087 | Biological process | regulation of respiratory gaseous exchange by nervous system process |
GO_0021527 | Biological process | spinal cord association neuron differentiation |
GO_0021575 | Biological process | hindbrain morphogenesis |
GO_0007219 | Biological process | Notch signaling pathway |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0021978 | Biological process | telencephalon regionalization |
GO_0048665 | Biological process | neuron fate specification |
GO_0021798 | Biological process | forebrain dorsal/ventral pattern formation |
GO_0097154 | Biological process | GABAergic neuron differentiation |
GO_0060163 | Biological process | subpallium neuron fate commitment |
GO_0030334 | Biological process | regulation of cell migration |
GO_0048714 | Biological process | positive regulation of oligodendrocyte differentiation |
GO_0021889 | Biological process | olfactory bulb interneuron differentiation |
GO_0045747 | Biological process | positive regulation of Notch signaling pathway |
GO_0048853 | Biological process | forebrain morphogenesis |
GO_0005737 | Cellular component | cytoplasm |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
Gene name | GSX2 |
Protein name | GS homeobox 2 GS homeobox 2 (Genetic-screened homeobox 2) (Homeobox protein GSH-2) |
Synonyms | GSH2 |
Description | FUNCTION: Transcription factor that binds 5'-CNAATTAG-3' DNA sequence and regulates the expression of numerous genes including genes important for brain development . During telencephalic development, causes ventralization of pallial progenitors and, depending on the developmental stage, specifies different neuronal fates. At early stages, necessary and sufficient to correctly specify the ventral lateral ganglionic eminence (LGE) and its major derivatives, the striatal projection neurons. At later stages, may specify LGE progenitors toward dorsal LGE fates, including olfactory bulb interneurons (By similarity). . |
Accessions | Q9BZM3 D6R903 ENST00000503800.1 B2LYG3 ENST00000326902.7 |