Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 14 studies | 56% ± 19% | |
| epithelial cell | 8 studies | 49% ± 12% | |
| enterocyte | 8 studies | 57% ± 25% | |
| club cell | 6 studies | 47% ± 14% | |
| respiratory goblet cell | 6 studies | 44% ± 15% | |
| epithelial cell of proximal tubule | 5 studies | 72% ± 11% | |
| deuterosomal cell | 4 studies | 24% ± 3% | |
| secretory cell | 4 studies | 39% ± 9% | |
| progenitor cell | 4 studies | 49% ± 18% | |
| basal cell | 4 studies | 31% ± 15% | |
| duct epithelial cell | 3 studies | 55% ± 10% | |
| goblet cell | 3 studies | 24% ± 6% | |
| intestinal crypt stem cell | 3 studies | 32% ± 6% | |
| transit amplifying cell | 3 studies | 23% ± 3% | |
| hepatocyte | 3 studies | 61% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 93% | 16892.29 | 210 / 226 | 86% | 1152.62 | 348 / 406 |
| kidney | 93% | 8646.64 | 83 / 89 | 58% | 347.39 | 526 / 901 |
| pancreas | 100% | 2971.54 | 327 / 328 | 37% | 36.50 | 66 / 178 |
| adrenal gland | 100% | 28656.78 | 258 / 258 | 33% | 521.45 | 76 / 230 |
| stomach | 73% | 2776.62 | 263 / 359 | 19% | 26.21 | 55 / 286 |
| ovary | 77% | 2110.09 | 138 / 180 | 11% | 19.79 | 46 / 430 |
| lung | 33% | 453.67 | 192 / 578 | 40% | 127.08 | 463 / 1155 |
| prostate | 44% | 473.76 | 107 / 245 | 14% | 15.22 | 69 / 502 |
| intestine | 29% | 1646.80 | 280 / 966 | 10% | 14.69 | 51 / 527 |
| esophagus | 9% | 51.14 | 133 / 1445 | 25% | 65.10 | 46 / 183 |
| bladder | 10% | 54.33 | 2 / 21 | 17% | 46.42 | 85 / 504 |
| breast | 19% | 149.89 | 85 / 459 | 6% | 10.22 | 64 / 1118 |
| tonsil | 0% | 0 | 0 / 0 | 16% | 74.11 | 7 / 45 |
| uterus | 3% | 22.04 | 5 / 170 | 9% | 28.95 | 41 / 459 |
| peripheral blood | 5% | 53.93 | 50 / 929 | 0% | 0 | 0 / 0 |
| skin | 2% | 6.63 | 34 / 1809 | 0% | 1.07 | 1 / 472 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.46 | 1 / 80 |
| thymus | 0% | 1.21 | 2 / 653 | 0% | 0.26 | 1 / 605 |
| blood vessel | 0% | 1.98 | 6 / 1335 | 0% | 0 | 0 / 0 |
| spleen | 0% | 1.77 | 1 / 241 | 0% | 0 | 0 / 0 |
| heart | 0% | 1.13 | 3 / 861 | 0% | 0 | 0 / 0 |
| adipose | 0% | 1.27 | 4 / 1204 | 0% | 0 | 0 / 0 |
| brain | 0% | 1.50 | 5 / 2642 | 0% | 0 | 0 / 705 |
| muscle | 0% | 0.34 | 1 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_1901687 | Biological process | glutathione derivative biosynthetic process |
| GO_0006805 | Biological process | xenobiotic metabolic process |
| GO_0098869 | Biological process | cellular oxidant detoxification |
| GO_0043651 | Biological process | linoleic acid metabolic process |
| GO_0006693 | Biological process | prostaglandin metabolic process |
| GO_0006749 | Biological process | glutathione metabolic process |
| GO_0030855 | Biological process | epithelial cell differentiation |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0004769 | Molecular function | steroid delta-isomerase activity |
| GO_0005504 | Molecular function | fatty acid binding |
| GO_0004602 | Molecular function | glutathione peroxidase activity |
| GO_0004364 | Molecular function | glutathione transferase activity |
| Gene name | GSTA1 |
| Protein name | Glutathione S-transferase A1 (EC 2.5.1.18) (13-hydroperoxyoctadecadienoate peroxidase) (EC 1.11.1.-) (Androst-5-ene-3,17-dione isomerase) (EC 5.3.3.-) (GST HA subunit 1) (GST class-alpha member 1) (GST-epsilon) (GSTA1-1) (GTH1) [Cleaved into: Glutathione S-transferase A1, N-terminally processed] |
| Synonyms | |
| Description | FUNCTION: Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2) . It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis . Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid . . |
| Accessions | P08263 ENST00000334575.6 |