I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 29% ± 4% | |
| dendritic cell | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 29% ± 4% | |
| dendritic cell | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of GRWD1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1895.31 | 1445 / 1445 | 100% | 27.92 | 183 / 183 |
| liver | 100% | 1491.38 | 226 / 226 | 100% | 20.00 | 406 / 406 |
| pancreas | 100% | 1370.61 | 328 / 328 | 100% | 25.40 | 178 / 178 |
| prostate | 100% | 2034.95 | 245 / 245 | 100% | 27.55 | 502 / 502 |
| skin | 100% | 2725.41 | 1809 / 1809 | 100% | 41.75 | 472 / 472 |
| breast | 100% | 2105.91 | 459 / 459 | 100% | 30.26 | 1117 / 1118 |
| intestine | 100% | 1614.47 | 966 / 966 | 100% | 30.48 | 526 / 527 |
| bladder | 100% | 2071.57 | 21 / 21 | 100% | 30.77 | 503 / 504 |
| uterus | 100% | 2075.72 | 170 / 170 | 100% | 35.12 | 458 / 459 |
| ovary | 100% | 1797.98 | 180 / 180 | 100% | 21.41 | 429 / 430 |
| stomach | 100% | 1563.04 | 359 / 359 | 100% | 28.93 | 285 / 286 |
| thymus | 100% | 1906.99 | 653 / 653 | 100% | 24.35 | 602 / 605 |
| lung | 100% | 1599.24 | 577 / 578 | 100% | 26.37 | 1150 / 1155 |
| kidney | 100% | 1572.79 | 89 / 89 | 99% | 19.28 | 895 / 901 |
| brain | 98% | 958.49 | 2599 / 2642 | 100% | 18.67 | 704 / 705 |
| adrenal gland | 100% | 1942.85 | 258 / 258 | 97% | 16.90 | 223 / 230 |
| adipose | 100% | 2093.51 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1543.06 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 37.19 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 45.11 | 29 / 29 |
| muscle | 100% | 2049.75 | 803 / 803 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2061.23 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 34.20 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 14.80 | 1 / 1 |
| heart | 99% | 1176.44 | 849 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 73% | 1079.56 | 674 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006334 | Biological process | nucleosome assembly |
| GO_0006337 | Biological process | nucleosome disassembly |
| GO_0042254 | Biological process | ribosome biogenesis |
| GO_0006260 | Biological process | DNA replication |
| GO_0005730 | Cellular component | nucleolus |
| GO_0032991 | Cellular component | protein-containing complex |
| GO_0005694 | Cellular component | chromosome |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| GO_0042393 | Molecular function | histone binding |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0003688 | Molecular function | DNA replication origin binding |
| GO_0003723 | Molecular function | RNA binding |
| Gene name | GRWD1 |
| Protein name | Glutamate-rich WD repeat-containing protein 1 Glutamate rich WD repeat containing 1 Alternative protein GRWD1 |
| Synonyms | WDR28 GRWD KIAA1942 |
| Description | FUNCTION: Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness . . |
| Accessions | L8EB83 M0QX71 ENST00000598711.1 ENST00000253237.10 Q9BQ67 |
