Name | Number of supported studies | Average coverage | |
---|---|---|---|
retinal cone cell | 7 studies | 55% ± 23% |
Insufficient scRNA-seq data for expression of GRK7 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 99% | 13.94 | 178 / 180 | 0% | 0 | 0 / 430 |
muscle | 98% | 20.42 | 788 / 803 | 0% | 0 | 0 / 0 |
spleen | 98% | 12.28 | 235 / 241 | 0% | 0 | 0 / 0 |
bladder | 95% | 7.14 | 20 / 21 | 1% | 0.03 | 4 / 504 |
lung | 93% | 9.49 | 537 / 578 | 3% | 0.07 | 32 / 1155 |
uterus | 95% | 9.91 | 162 / 170 | 0% | 0.00 | 1 / 459 |
prostate | 94% | 9.92 | 231 / 245 | 0% | 0 | 0 / 502 |
adrenal gland | 88% | 6.56 | 228 / 258 | 0% | 0.00 | 1 / 230 |
blood vessel | 88% | 7.42 | 1181 / 1335 | 0% | 0 | 0 / 0 |
adipose | 88% | 7.75 | 1063 / 1204 | 0% | 0 | 0 / 0 |
brain | 88% | 8.58 | 2322 / 2642 | 0% | 0.00 | 2 / 705 |
breast | 88% | 7.33 | 402 / 459 | 0% | 0.00 | 2 / 1118 |
skin | 87% | 10.25 | 1575 / 1809 | 0% | 0 | 0 / 472 |
thymus | 86% | 6.06 | 564 / 653 | 0% | 0 | 0 / 605 |
intestine | 85% | 6.07 | 817 / 966 | 0% | 0.01 | 2 / 527 |
kidney | 84% | 5.25 | 75 / 89 | 0% | 0.00 | 1 / 901 |
esophagus | 78% | 4.53 | 1120 / 1445 | 6% | 0.12 | 11 / 183 |
heart | 77% | 4.39 | 663 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 70% | 4.88 | 654 / 929 | 0% | 0 | 0 / 0 |
stomach | 62% | 4.34 | 224 / 359 | 1% | 0.01 | 2 / 286 |
pancreas | 57% | 2.38 | 187 / 328 | 1% | 0.01 | 1 / 178 |
liver | 49% | 2.05 | 110 / 226 | 0% | 0 | 0 / 406 |
eye | 0% | 0 | 0 / 0 | 1% | 0.04 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0009966 | Biological process | regulation of signal transduction |
GO_0007601 | Biological process | visual perception |
GO_0006468 | Biological process | protein phosphorylation |
GO_0046777 | Biological process | protein autophosphorylation |
GO_0022400 | Biological process | regulation of opsin-mediated signaling pathway |
GO_0097381 | Cellular component | photoreceptor disc membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0050254 | Molecular function | rhodopsin kinase activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | GRK7 |
Protein name | Rhodopsin kinase GRK7 (EC 2.7.11.14) (G protein-coupled receptor kinase 7) (G protein-coupled receptor kinase GRK7) |
Synonyms | GPRK7 |
Description | FUNCTION: Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO). . |
Accessions | ENST00000682958.1 Q8WTQ7 ENST00000264952.2 |