Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| macrophage | 7 studies | 26% ± 11% | |
| epithelial cell | 4 studies | 22% ± 5% | |
| astrocyte | 4 studies | 29% ± 6% | |
| myeloid cell | 3 studies | 20% ± 3% | |
| GABAergic neuron | 3 studies | 30% ± 4% | |
| glutamatergic neuron | 3 studies | 40% ± 12% | |
| dendritic cell | 3 studies | 21% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 3 studies | 30% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2585.06 | 1444 / 1445 | 100% | 37.17 | 183 / 183 |
| intestine | 100% | 3668.70 | 966 / 966 | 99% | 38.39 | 524 / 527 |
| breast | 100% | 2162.65 | 459 / 459 | 99% | 32.31 | 1110 / 1118 |
| thymus | 100% | 3852.57 | 653 / 653 | 99% | 38.16 | 600 / 605 |
| lung | 99% | 2538.48 | 575 / 578 | 99% | 41.80 | 1146 / 1155 |
| brain | 99% | 2162.32 | 2615 / 2642 | 100% | 37.60 | 703 / 705 |
| stomach | 100% | 2526.33 | 359 / 359 | 99% | 35.91 | 282 / 286 |
| kidney | 100% | 1955.64 | 89 / 89 | 98% | 49.29 | 886 / 901 |
| uterus | 100% | 1406.91 | 170 / 170 | 97% | 37.45 | 446 / 459 |
| skin | 98% | 3695.41 | 1768 / 1809 | 99% | 52.08 | 469 / 472 |
| pancreas | 99% | 1680.68 | 324 / 328 | 98% | 32.58 | 175 / 178 |
| liver | 100% | 15125.89 | 226 / 226 | 94% | 38.62 | 382 / 406 |
| bladder | 100% | 1430.86 | 21 / 21 | 92% | 26.95 | 464 / 504 |
| ovary | 100% | 1848.17 | 180 / 180 | 91% | 16.69 | 390 / 430 |
| adrenal gland | 100% | 7547.46 | 258 / 258 | 81% | 15.64 | 186 / 230 |
| prostate | 100% | 2586.73 | 245 / 245 | 73% | 13.86 | 367 / 502 |
| adipose | 100% | 2261.25 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 2802.56 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 49.06 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.24 | 1 / 1 |
| heart | 100% | 3872.20 | 859 / 861 | 0% | 0 | 0 / 0 |
| muscle | 100% | 2356.78 | 801 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 35.26 | 79 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 23.69 | 28 / 29 |
| blood vessel | 83% | 879.60 | 1108 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 80% | 907.18 | 741 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006915 | Biological process | apoptotic process |
| GO_0043280 | Biological process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process |
| GO_0034164 | Biological process | negative regulation of toll-like receptor 9 signaling pathway |
| GO_0031966 | Cellular component | mitochondrial membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005515 | Molecular function | protein binding |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | GRAMD4 |
| Protein name | GRAM domain containing 4 GRAM domain-containing protein 4 (Death-inducing protein) |
| Synonyms | DIP KIAA0767 |
| Description | FUNCTION: Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53 . Plays a role as a mediator of E2F1-induced apoptosis in the absence of p53/TP53. Inhibits TLR9 response to nucelic acids and regulates TLR9-mediated innate immune response (By similarity). . |
| Accessions | ENST00000431155.1 ENST00000447351.5 ENST00000408031.1 [Q6IC98-2] Q6IC98 X6RHZ2 H0Y5A3 X6RIP6 ENST00000406902.6 [Q6IC98-1] ENST00000361034.7 [Q6IC98-1] ENST00000456069.1 |
