GPSM2 | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	15 studies	39% ± 21%	Explore
oligodendrocyte	13 studies	35% ± 16%	Explore
astrocyte	10 studies	33% ± 15%	Explore
GABAergic neuron	6 studies	29% ± 9%	Explore
epithelial cell	4 studies	20% ± 6%	Explore
retinal cone cell	4 studies	32% ± 7%	Explore
fibroblast	4 studies	24% ± 6%	Explore
glutamatergic neuron	4 studies	31% ± 8%	Explore
interneuron	4 studies	35% ± 16%	Explore

Name	Number of supported studies	Average coverage
brain	8 studies	33% ± 15%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2265.01	1445 / 1445	100%	7.60	183 / 183
brain	100%	1579.32	2638 / 2642	100%	8.58	702 / 705
intestine	100%	1495.00	966 / 966	99%	8.56	522 / 527
lung	100%	1174.76	577 / 578	96%	3.91	1110 / 1155
uterus	100%	855.46	170 / 170	96%	6.13	439 / 459
breast	99%	711.58	454 / 459	95%	4.09	1066 / 1118
bladder	100%	606.57	21 / 21	93%	5.53	469 / 504
stomach	88%	542.84	316 / 359	98%	8.49	281 / 286
skin	100%	2493.35	1809 / 1809	84%	2.79	396 / 472
ovary	91%	457.68	164 / 180	92%	2.92	394 / 430
prostate	99%	801.16	243 / 245	45%	0.68	224 / 502
pancreas	55%	207.38	179 / 328	75%	1.72	134 / 178
adrenal gland	93%	459.48	239 / 258	18%	0.41	41 / 230
thymus	94%	510.84	615 / 653	16%	0.42	97 / 605
tonsil	0%	0	0 / 0	98%	8.44	44 / 45
adipose	95%	659.00	1138 / 1204	0%	0	0 / 0
muscle	90%	694.64	725 / 803	0%	0	0 / 0
blood vessel	88%	450.38	1174 / 1335	0%	0	0 / 0
kidney	40%	185.06	36 / 89	47%	1.12	422 / 901
spleen	80%	348.96	193 / 241	0%	0	0 / 0
liver	33%	111.53	75 / 226	22%	0.47	89 / 406
heart	53%	242.34	455 / 861	0%	0	0 / 0
lymph node	0%	0	0 / 0	52%	1.04	15 / 29
peripheral blood	37%	322.93	343 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	5%	0.06	4 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007052	Biological process	mitotic spindle organization
GO_0000132	Biological process	establishment of mitotic spindle orientation
GO_0051301	Biological process	cell division
GO_1905832	Biological process	positive regulation of spindle assembly
GO_0051661	Biological process	maintenance of centrosome location
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_1904778	Biological process	positive regulation of protein localization to cell cortex
GO_0060236	Biological process	regulation of mitotic spindle organization
GO_0097431	Cellular component	mitotic spindle pole
GO_0099738	Cellular component	cell cortex region
GO_0005813	Cellular component	centrosome
GO_0097575	Cellular component	lateral cell cortex
GO_0032991	Cellular component	protein-containing complex
GO_0005829	Cellular component	cytosol
GO_0005938	Cellular component	cell cortex
GO_0016328	Cellular component	lateral plasma membrane
GO_0005737	Cellular component	cytoplasm
GO_0005092	Molecular function	GDP-dissociation inhibitor activity
GO_0019904	Molecular function	protein domain specific binding
GO_0001965	Molecular function	G-protein alpha-subunit binding
GO_0042802	Molecular function	identical protein binding
GO_0000166	Molecular function	nucleotide binding
GO_0070840	Molecular function	dynein complex binding
GO_0005515	Molecular function	protein binding

Gene name	GPSM2
Protein name	G protein signaling modulator 2 G-protein-signaling modulator 2 G-protein-signaling modulator 2 (Mosaic protein LGN)
Synonyms	LGN
Description	FUNCTION: Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 . Required for cortical dynein-dynactin complex recruitment during metaphase . Plays a role in metaphase spindle orientation . Also plays an important role in asymmetric cell divisions . Has guanine nucleotide dissociation inhibitor (GDI) activity towards G(i) alpha proteins, such as GNAI1 and GNAI3, and thereby regulates their activity (By similarity). .
Accessions	B0QZC9 A0A2R8Y673 ENST00000446797 ENST00000645164 B0QZD0 ENST00000645164.2 ENST00000676184.1 ENST00000674731.1 A0A6Q8PF02 P81274 A0A6Q8PGS6 ENST00000674914.1 A0A6Q8PGU2 A0A2R8Y6E3 A0A6Q8PFD2 ENST00000643643.1 ENST00000435987.5 ENST00000264126.9 ENST00000675087.1 ENST00000441735.2 A0A2R8YCX1 ENST00000643094.1 ENST00000406462.6 ENST00000642355.1 A0A6Q8PGW7 A0A2R8Y896 H0Y4A4 ENST00000645255.1 ENST00000675086.1 ENST00000674700.1 ENST00000446797.2 Q5T1N9 ENST00000676404.1 ENST00000435475.5

GPSM2 report