Insufficient scRNA-seq data for expression of GPR88 at single-cell level.
Insufficient scRNA-seq data for expression of GPR88 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 94% | 391.05 | 213 / 226 | 58% | 31.68 | 237 / 406 |
brain | 75% | 2705.42 | 1971 / 2642 | 76% | 4.79 | 537 / 705 |
spleen | 100% | 589.63 | 241 / 241 | 0% | 0 | 0 / 0 |
ovary | 92% | 292.82 | 165 / 180 | 5% | 0.15 | 20 / 430 |
breast | 73% | 271.14 | 333 / 459 | 13% | 1.72 | 142 / 1118 |
intestine | 68% | 107.55 | 660 / 966 | 3% | 0.07 | 17 / 527 |
esophagus | 62% | 132.51 | 894 / 1445 | 5% | 0.10 | 9 / 183 |
blood vessel | 58% | 110.38 | 773 / 1335 | 0% | 0 | 0 / 0 |
adipose | 53% | 52.26 | 636 / 1204 | 0% | 0 | 0 / 0 |
prostate | 12% | 11.30 | 30 / 245 | 27% | 1.41 | 135 / 502 |
stomach | 28% | 34.30 | 101 / 359 | 8% | 0.17 | 24 / 286 |
thymus | 27% | 19.89 | 177 / 653 | 9% | 1.10 | 54 / 605 |
kidney | 21% | 14.51 | 19 / 89 | 9% | 0.24 | 78 / 901 |
uterus | 21% | 20.05 | 35 / 170 | 9% | 0.32 | 40 / 459 |
adrenal gland | 20% | 12.08 | 52 / 258 | 7% | 0.16 | 16 / 230 |
heart | 24% | 19.76 | 205 / 861 | 0% | 0 | 0 / 0 |
lung | 13% | 9.52 | 73 / 578 | 11% | 0.29 | 123 / 1155 |
muscle | 20% | 19.20 | 159 / 803 | 0% | 0 | 0 / 0 |
pancreas | 1% | 0.70 | 4 / 328 | 6% | 0.22 | 11 / 178 |
bladder | 5% | 2.48 | 1 / 21 | 3% | 0.07 | 13 / 504 |
skin | 1% | 0.93 | 25 / 1809 | 4% | 0.08 | 19 / 472 |
eye | 0% | 0 | 0 / 0 | 4% | 0.07 | 3 / 80 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.04 | 1 / 29 |
peripheral blood | 1% | 0.46 | 7 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0050885 | Biological process | neuromuscular process controlling balance |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007188 | Biological process | adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
GO_0007602 | Biological process | phototransduction |
GO_0009584 | Biological process | detection of visible light |
GO_0071482 | Biological process | cellular response to light stimulus |
GO_0071875 | Biological process | adrenergic receptor signaling pathway |
GO_0019228 | Biological process | neuronal action potential |
GO_0061743 | Biological process | motor learning |
GO_0007626 | Biological process | locomotory behavior |
GO_0060170 | Cellular component | ciliary membrane |
GO_0005929 | Cellular component | cilium |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0003774 | Molecular function | cytoskeletal motor activity |
GO_0008020 | Molecular function | G protein-coupled photoreceptor activity |
GO_0004941 | Molecular function | beta2-adrenergic receptor activity |
Gene name | GPR88 |
Protein name | G protein-coupled receptor 88 (Striatum-specific G-protein coupled receptor) |
Synonyms | STRG |
Description | FUNCTION: Orphan G protein-coupled receptor implicated in a large repertoire of behavioral responses that engage motor activities, spatial learning, and emotional processing (By similarity). May play a role in the regulation of cognitive and motor function (By similarity). Couples with the heterotrimeric G protein complex of the G(i) subfamily, consisting of GNAI1, GNB1 and GNG2, thereby acting through a G(i)-mediated pathway . Plays a role in the attenuation of D1 dopamine receptor (D1R)-mediated cAMP response in ciliated cells . In non-ciliated cells, involved in the inhibition of the beta-2 adrenergic receptor (B2AR) response . . |
Accessions | Q9GZN0 ENST00000315033.5 |