Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 20 studies | 25% ± 8% | |
| astrocyte | 11 studies | 31% ± 12% | |
| retinal rod cell | 9 studies | 36% ± 15% | |
| dendritic cell | 8 studies | 29% ± 8% | |
| myeloid cell | 7 studies | 28% ± 9% | |
| monocyte | 6 studies | 20% ± 4% | |
| non-classical monocyte | 5 studies | 24% ± 7% | |
| microglial cell | 5 studies | 23% ± 4% | |
| Mueller cell | 5 studies | 39% ± 13% | |
| oligodendrocyte precursor cell | 5 studies | 30% ± 12% | |
| amacrine cell | 4 studies | 24% ± 7% | |
| retina horizontal cell | 4 studies | 23% ± 9% | |
| mononuclear phagocyte | 4 studies | 23% ± 6% | |
| GABAergic neuron | 4 studies | 38% ± 11% | |
| glutamatergic neuron | 4 studies | 39% ± 13% | |
| interneuron | 4 studies | 36% ± 16% | |
| oligodendrocyte | 4 studies | 21% ± 3% | |
| epithelial cell of proximal tubule | 3 studies | 18% ± 2% | |
| retinal cone cell | 3 studies | 22% ± 5% | |
| retinal pigment epithelial cell | 3 studies | 33% ± 12% | |
| glycinergic amacrine cell | 3 studies | 28% ± 6% | |
| conventional dendritic cell | 3 studies | 20% ± 4% | |
| alveolar macrophage | 3 studies | 29% ± 7% | |
| melanocyte | 3 studies | 42% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 2238.53 | 2642 / 2642 | 100% | 114.31 | 705 / 705 |
| skin | 100% | 1614.42 | 1806 / 1809 | 100% | 196.00 | 472 / 472 |
| kidney | 100% | 2354.84 | 89 / 89 | 98% | 68.96 | 886 / 901 |
| breast | 99% | 918.56 | 453 / 459 | 97% | 59.45 | 1087 / 1118 |
| bladder | 100% | 1619.62 | 21 / 21 | 96% | 36.47 | 482 / 504 |
| lung | 99% | 1215.14 | 575 / 578 | 96% | 38.40 | 1107 / 1155 |
| esophagus | 95% | 583.28 | 1377 / 1445 | 97% | 35.69 | 178 / 183 |
| thymus | 99% | 907.53 | 648 / 653 | 93% | 36.38 | 562 / 605 |
| intestine | 99% | 995.43 | 960 / 966 | 88% | 23.29 | 465 / 527 |
| uterus | 99% | 1405.05 | 168 / 170 | 88% | 27.88 | 406 / 459 |
| prostate | 100% | 1066.78 | 245 / 245 | 87% | 27.40 | 438 / 502 |
| ovary | 98% | 897.33 | 176 / 180 | 88% | 28.46 | 378 / 430 |
| stomach | 86% | 473.79 | 308 / 359 | 90% | 29.25 | 258 / 286 |
| liver | 69% | 377.51 | 155 / 226 | 64% | 19.61 | 261 / 406 |
| adrenal gland | 93% | 570.74 | 239 / 258 | 30% | 6.71 | 68 / 230 |
| pancreas | 19% | 81.76 | 62 / 328 | 95% | 34.62 | 169 / 178 |
| eye | 0% | 0 | 0 / 0 | 100% | 265.82 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 69.33 | 29 / 29 |
| spleen | 100% | 1531.39 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 36.51 | 1 / 1 |
| adipose | 100% | 1205.69 | 1199 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 968.55 | 1308 / 1335 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 31.14 | 43 / 45 |
| heart | 95% | 1450.46 | 814 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 69% | 838.98 | 637 / 929 | 0% | 0 | 0 / 0 |
| muscle | 4% | 14.20 | 29 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006914 | Biological process | autophagy |
| GO_0043030 | Biological process | regulation of macrophage activation |
| GO_0010506 | Biological process | regulation of autophagy |
| GO_0043087 | Biological process | regulation of GTPase activity |
| GO_1904263 | Biological process | positive regulation of TORC1 signaling |
| GO_0150032 | Biological process | positive regulation of protein localization to lysosome |
| GO_0045779 | Biological process | negative regulation of bone resorption |
| GO_0045671 | Biological process | negative regulation of osteoclast differentiation |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005765 | Cellular component | lysosomal membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GPR137B |
| Protein name | Integral membrane protein GPR137B (Transmembrane 7 superfamily member 1 protein) G protein-coupled receptor 137B |
| Synonyms | TM7SF1 |
| Description | FUNCTION: Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids . Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome . Involved in the regulation of lysosomal morphology and autophagy . .; FUNCTION: Acts also as a negative regulator of osteoclast activity (By similarity). Involved in interleukin-4-induced M2 macrophage polarization (By similarity). . |
| Accessions | ENST00000454895.2 ENST00000419162.5 Q5TAF0 O60478 ENST00000366592.8 H0Y509 |