I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 14 studies | 52% ± 18% | |
| epithelial cell | 5 studies | 27% ± 9% | |
| deuterosomal cell | 3 studies | 17% ± 1% | |
| basal cell | 3 studies | 42% ± 29% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 14 studies | 52% ± 18% | |
| epithelial cell | 5 studies | 27% ± 9% | |
| deuterosomal cell | 3 studies | 17% ± 1% | |
| basal cell | 3 studies | 42% ± 29% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| lung | 3 studies | 21% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 311.18 | 1445 / 1445 | 100% | 26.42 | 183 / 183 |
| ovary | 100% | 263.31 | 180 / 180 | 100% | 46.01 | 430 / 430 |
| prostate | 100% | 408.99 | 245 / 245 | 100% | 36.06 | 502 / 502 |
| stomach | 100% | 339.31 | 359 / 359 | 100% | 30.55 | 286 / 286 |
| brain | 100% | 365.59 | 2638 / 2642 | 100% | 29.63 | 705 / 705 |
| breast | 100% | 335.08 | 459 / 459 | 100% | 38.97 | 1115 / 1118 |
| pancreas | 100% | 277.55 | 327 / 328 | 100% | 28.60 | 178 / 178 |
| thymus | 100% | 398.87 | 653 / 653 | 100% | 31.47 | 603 / 605 |
| kidney | 100% | 614.29 | 89 / 89 | 100% | 27.64 | 898 / 901 |
| lung | 100% | 426.72 | 576 / 578 | 100% | 33.17 | 1155 / 1155 |
| intestine | 100% | 484.17 | 966 / 966 | 100% | 31.46 | 525 / 527 |
| bladder | 100% | 330.76 | 21 / 21 | 100% | 29.94 | 502 / 504 |
| uterus | 99% | 299.27 | 169 / 170 | 100% | 40.33 | 459 / 459 |
| liver | 100% | 299.49 | 226 / 226 | 99% | 23.30 | 403 / 406 |
| adrenal gland | 100% | 617.88 | 258 / 258 | 99% | 30.05 | 227 / 230 |
| skin | 99% | 314.93 | 1797 / 1809 | 97% | 29.23 | 459 / 472 |
| adipose | 100% | 313.41 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 54.97 | 29 / 29 |
| spleen | 100% | 428.34 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 30.08 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 20.75 | 1 / 1 |
| muscle | 100% | 371.64 | 801 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 270.82 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| heart | 98% | 386.77 | 844 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 95% | 21.67 | 76 / 80 |
| peripheral blood | 70% | 247.67 | 650 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0002949 | Biological process | tRNA threonylcarbamoyladenosine modification |
| GO_0000408 | Cellular component | EKC/KEOPS complex |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GON7 |
| Protein name | EKC/KEOPS complex subunit GON7 EKC/KEOPS complex subunit GON7 (GON7 subunit of KEOPS complex) |
| Synonyms | C14orf142 |
| Description | FUNCTION: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine . The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 . GON7 plays a supporting role to the catalytic subunit OSGEP in the complex . . |
| Accessions | Q9BXV9 ENST00000621279.2 ENST00000556566.1 H0YJA8 ENST00000306954.5 ENST00000629526.1 |
