GMPR2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046037Biological processGMP metabolic process
GO_0006144Biological processpurine nucleobase metabolic process
GO_1902560Cellular componentGMP reductase complex
GO_0005829Cellular componentcytosol
GO_0003920Molecular functionGMP reductase activity
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameGMPR2
Protein nameGMP reductase (EC 1.7.1.7)
GMP reductase (GMPR) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase) (Guanosine monophosphate reductase)
Guanosine monophosphate reductase 2
GMP reductase 2 (GMPR 2) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 2) (Guanosine monophosphate reductase 2)
SynonymsGMPR
hCG_40198
DescriptionFUNCTION: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides . Plays a role in modulating cellular differentiation . .

FUNCTION: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. .

FUNCTION: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. .

FUNCTION: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. .

FUNCTION: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. .

AccessionsH0YNS9
ENST00000647320.3 [Q9P2T1-1]
H0YMG3
H0YNJ6
H0YL68
ENST00000559287.5
ENST00000642276.1 [Q9P2T1-1]
ENST00000559409.5
A0A0B4J281
H0YKK3
ENST00000557854.5
ENST00000399440.7 [Q9P2T1-1]
ENST00000558483.5
ENST00000559836.5 [Q9P2T1-1]
ENST00000420554.6 [Q9P2T1-2]
H0YMW6
H0YK13
H0YN22
ENST00000558748.1
Q6PKC0
H0YN74
ENST00000558788.1
ENST00000645781.1 [Q9P2T1-2]
H0YKE1
ENST00000558932.1
H0YLB8
H0YMR9
ENST00000560139.5
ENST00000644066.1 [Q9P2T1-1]
H0YLV5
H0YK71
ENST00000559102.1
H0YMV5
ENST00000561035.5
ENST00000355299.8 [Q9P2T1-1]
ENST00000561130.5
ENST00000643803.1 [Q9P2T1-3]
ENST00000456667.7 [Q9P2T1-3]
H0YNH0
ENST00000561038.5
ENST00000559104.5
ENST00000558279.5
Q86SZ5
Q9P2T1
ENST00000558865.5
ENST00000559910.5
H0YMB3
ENST00000559943.1
ENST00000558760.5
ENST00000559479.1