I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| plasma cell | 5 studies | 27% ± 11% | |
| epithelial cell | 4 studies | 26% ± 7% | |
| goblet cell | 4 studies | 23% ± 3% | |
| dendritic cell | 3 studies | 17% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| plasma cell | 5 studies | 27% ± 11% | |
| epithelial cell | 4 studies | 26% ± 7% | |
| goblet cell | 4 studies | 23% ± 3% | |
| dendritic cell | 3 studies | 17% ± 1% |
Insufficient scRNA-seq data for expression of GMPPA at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1758.53 | 1445 / 1445 | 100% | 28.07 | 183 / 183 |
| intestine | 100% | 2249.16 | 966 / 966 | 100% | 34.92 | 527 / 527 |
| liver | 100% | 2930.78 | 226 / 226 | 100% | 33.85 | 406 / 406 |
| ovary | 100% | 1930.16 | 180 / 180 | 100% | 27.04 | 430 / 430 |
| pancreas | 100% | 2814.61 | 328 / 328 | 100% | 31.76 | 178 / 178 |
| prostate | 100% | 3633.59 | 245 / 245 | 100% | 47.21 | 502 / 502 |
| skin | 100% | 1975.08 | 1809 / 1809 | 100% | 35.67 | 472 / 472 |
| stomach | 100% | 2079.99 | 359 / 359 | 100% | 32.93 | 286 / 286 |
| thymus | 100% | 2935.77 | 653 / 653 | 100% | 24.45 | 605 / 605 |
| lung | 100% | 2007.87 | 577 / 578 | 100% | 30.42 | 1155 / 1155 |
| uterus | 100% | 2645.24 | 170 / 170 | 100% | 32.08 | 458 / 459 |
| breast | 100% | 2013.93 | 459 / 459 | 100% | 33.54 | 1115 / 1118 |
| bladder | 100% | 2270.81 | 21 / 21 | 100% | 29.64 | 502 / 504 |
| kidney | 100% | 1949.18 | 89 / 89 | 100% | 23.36 | 897 / 901 |
| adrenal gland | 100% | 2086.36 | 258 / 258 | 99% | 20.48 | 228 / 230 |
| brain | 98% | 1057.29 | 2602 / 2642 | 100% | 25.99 | 705 / 705 |
| adipose | 100% | 1832.99 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 28.42 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 37.53 | 29 / 29 |
| spleen | 100% | 3086.37 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 26.89 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 24.58 | 1 / 1 |
| blood vessel | 100% | 2147.39 | 1332 / 1335 | 0% | 0 | 0 / 0 |
| heart | 99% | 1607.47 | 855 / 861 | 0% | 0 | 0 / 0 |
| muscle | 99% | 1224.34 | 796 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 97% | 1522.67 | 905 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0009058 | Biological process | biosynthetic process |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0016740 | Molecular function | transferase activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GMPPA |
| Protein name | Mannose-1-phosphate guanyltransferase alpha (GDP-mannose pyrophosphorylase A) (GTP-mannose-1-phosphate guanylyltransferase alpha) GDP-mannose pyrophosphorylase A Mannose-1-phosphate guanyltransferase alpha (GDP-mannose pyrophosphorylase A) (GMPP-alpha) (GTP-mannose-1-phosphate guanylyltransferase alpha) |
| Synonyms | |
| Description | FUNCTION: May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. . FUNCTION: May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. . FUNCTION: May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. . FUNCTION: May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. . |
| Accessions | ENST00000373917.7 [Q96IJ6-2] ENST00000683591.1 ENST00000373908.5 [Q96IJ6-1] A0A804HLB2 ENST00000683131.1 A0A804HKA4 ENST00000341142.8 [Q96IJ6-1] C9JAH0 C9J255 ENST00000683626.1 ENST00000358215.8 [Q96IJ6-1] ENST00000683864.1 ENST00000683752.1 A0A804HIM4 ENST00000684729.1 ENST00000622191 ENST00000622191.2 [Q96IJ6-1] A0A804HJC3 ENST00000455657.6 ENST00000682488.1 A0A0U1RRC2 A0A087WUI8 ENST00000684669.1 ENST00000683598.1 ENST00000683386.1 B4DJR0 ENST00000435316.6 ENST00000682102.1 A0A804HIS0 ENST00000443704.5 ENST00000480034.1 ENST00000682576.1 A0A804HLK2 ENST00000313597.10 [Q96IJ6-1] A0A804HID2 ENST00000682058.1 F8WD54 Q96IJ6 ENST00000683946.1 [Q96IJ6-1] ENST00000683402.1 ENST00000682481.1 ENST00000684227.1 ENST00000683691.1 |
