Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| interneuron | 6 studies | 34% ± 15% | |
| GABAergic neuron | 6 studies | 42% ± 15% | |
| glutamatergic neuron | 4 studies | 33% ± 4% | |
| GABAergic interneuron | 3 studies | 27% ± 4% | |
| neuron | 3 studies | 27% ± 6% | |
| amacrine cell | 3 studies | 21% ± 3% | |
| GABAergic amacrine cell | 3 studies | 27% ± 4% | |
| glycinergic amacrine cell | 3 studies | 28% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 27% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 87% | 539.45 | 2291 / 2642 | 43% | 2.25 | 302 / 705 |
| intestine | 16% | 14.64 | 156 / 966 | 24% | 1.42 | 129 / 527 |
| stomach | 0% | 0.13 | 1 / 359 | 24% | 1.62 | 69 / 286 |
| ovary | 8% | 7.71 | 14 / 180 | 5% | 0.45 | 20 / 430 |
| skin | 1% | 1.00 | 19 / 1809 | 11% | 1.16 | 50 / 472 |
| bladder | 0% | 0 | 0 / 21 | 8% | 0.56 | 42 / 504 |
| uterus | 1% | 0.34 | 1 / 170 | 4% | 0.15 | 20 / 459 |
| kidney | 2% | 1.00 | 2 / 89 | 2% | 0.04 | 14 / 901 |
| pancreas | 0% | 0 | 0 / 328 | 3% | 0.11 | 5 / 178 |
| esophagus | 0% | 0.06 | 1 / 1445 | 3% | 0.13 | 5 / 183 |
| breast | 0% | 0.20 | 1 / 459 | 1% | 0.10 | 15 / 1118 |
| adrenal gland | 0% | 0.85 | 1 / 258 | 1% | 0.04 | 2 / 230 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.06 | 1 / 80 |
| lung | 0% | 0.71 | 2 / 578 | 1% | 0.03 | 9 / 1155 |
| spleen | 0% | 0.30 | 1 / 241 | 0% | 0 | 0 / 0 |
| prostate | 0% | 0 | 0 / 245 | 0% | 0.02 | 2 / 502 |
| thymus | 0% | 0.21 | 2 / 653 | 0% | 0 | 0 / 605 |
| adipose | 0% | 0.04 | 1 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.09 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| liver | 0% | 0 | 0 / 226 | 0% | 0 | 0 / 406 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007218 | Biological process | neuropeptide signaling pathway |
| GO_0042391 | Biological process | regulation of membrane potential |
| GO_0071361 | Biological process | cellular response to ethanol |
| GO_0060079 | Biological process | excitatory postsynaptic potential |
| GO_0034220 | Biological process | monoatomic ion transmembrane transport |
| GO_0071294 | Biological process | cellular response to zinc ion |
| GO_1902476 | Biological process | chloride transmembrane transport |
| GO_0007268 | Biological process | chemical synaptic transmission |
| GO_0071230 | Biological process | cellular response to amino acid stimulus |
| GO_0098690 | Cellular component | glycinergic synapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_1902495 | Cellular component | transmembrane transporter complex |
| GO_0043005 | Cellular component | neuron projection |
| GO_0034707 | Cellular component | chloride channel complex |
| GO_0045202 | Cellular component | synapse |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_1904315 | Molecular function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0005231 | Molecular function | excitatory extracellular ligand-gated monoatomic ion channel activity |
| GO_0016934 | Molecular function | extracellularly glycine-gated chloride channel activity |
| GO_0030594 | Molecular function | neurotransmitter receptor activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0016594 | Molecular function | glycine binding |
| GO_0022852 | Molecular function | glycine-gated chloride ion channel activity |
| GO_0005254 | Molecular function | chloride channel activity |
| Gene name | GLRA2 |
| Protein name | Glycine receptor alpha 2 Glycine receptor subunit alpha-2 |
| Synonyms | |
| Description | FUNCTION: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine . Channel opening is also triggered by taurine and beta-alanine . Plays a role in synaptic plasticity (By similarity). Contributes to the generation of inhibitory postsynaptic currents, and is involved in the down-regulation of neuronal excitability . Plays a role in cellular responses to ethanol . . |
| Accessions | ENST00000355020.9 [P23416-2] ENST00000443437.6 A0A9S7JRE2 P23416 ENST00000218075.9 [P23416-1] |
