GKAP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0046628Biological processpositive regulation of insulin receptor signaling pathway
GO_0005794Cellular componentGolgi apparatus
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGKAP1
Protein nameG kinase-anchoring protein 1 (cGMP-dependent protein kinase-anchoring protein of 42 kDa)
G kinase anchoring protein 1
SynonymsFKSG21
GKAP42
DescriptionFUNCTION: Regulates insulin-dependent IRS1 tyrosine phosphorylation in adipocytes by modulating the availability of IRS1 to IR tyrosine kinase. Its association with IRS1 is required for insulin-induced translocation of SLC2A4 to the cell membrane. Involved in TNF-induced impairment of insulin-dependent IRS1 tyrosine phosphorylation. .

AccessionsENST00000376371.7 [Q5VSY0-1]
B4DXS0
Q5VSY0
C9J9D2
ENST00000485742.5
ENST00000388782.8
ENST00000376365.7 [Q5VSY0-2]