GJC2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GJC2 at tissue level.

III. Associated gene sets

GO_2000134Biological processnegative regulation of G1/S transition of mitotic cell cycle
GO_0007267Biological processcell-cell signaling
GO_0010628Biological processpositive regulation of gene expression
GO_1904427Biological processpositive regulation of calcium ion transmembrane transport
GO_0070447Biological processpositive regulation of oligodendrocyte progenitor proliferation
GO_0010644Biological processcell communication by electrical coupling
GO_0009636Biological processresponse to toxic substance
GO_0001932Biological processregulation of protein phosphorylation
GO_0055085Biological processtransmembrane transport
GO_0043204Cellular componentperikaryon
GO_1990769Cellular componentproximal neuron projection
GO_0043209Cellular componentmyelin sheath
GO_0005922Cellular componentconnexin complex
GO_0033270Cellular componentparanode region of axon
GO_0005921Cellular componentgap junction
GO_0005243Molecular functiongap junction channel activity
GO_1903763Molecular functiongap junction channel activity involved in cell communication by electrical coupling

IV. Literature review

[source]
Gene nameGJC2
Protein nameGap junction gamma-2 protein (Connexin-46.6) (Cx46.6) (Connexin-47) (Cx47) (Gap junction alpha-12 protein)
GJA12
SynonymsGJA12
DescriptionFUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems. .

AccessionsQ5T442
ENST00000366714.3
B9U3U6