Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| fibroblast | 15 studies | 25% ± 10% | |
| mesothelial cell | 9 studies | 33% ± 21% | |
| connective tissue cell | 6 studies | 29% ± 10% | |
| smooth muscle cell | 5 studies | 22% ± 8% | |
| adventitial cell | 4 studies | 30% ± 6% |
Insufficient scRNA-seq data for expression of GAS1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ovary | 100% | 5878.94 | 180 / 180 | 97% | 84.35 | 418 / 430 |
| breast | 99% | 5482.37 | 456 / 459 | 91% | 33.71 | 1015 / 1118 |
| skin | 99% | 3708.21 | 1795 / 1809 | 90% | 25.49 | 423 / 472 |
| prostate | 96% | 3189.00 | 234 / 245 | 77% | 14.20 | 386 / 502 |
| uterus | 99% | 12920.87 | 168 / 170 | 70% | 42.52 | 322 / 459 |
| pancreas | 74% | 711.48 | 244 / 328 | 82% | 30.04 | 146 / 178 |
| esophagus | 76% | 2453.59 | 1103 / 1445 | 61% | 24.62 | 112 / 183 |
| bladder | 86% | 2895.62 | 18 / 21 | 45% | 11.17 | 225 / 504 |
| thymus | 91% | 2328.28 | 597 / 653 | 34% | 10.99 | 205 / 605 |
| lung | 63% | 1007.91 | 366 / 578 | 61% | 13.61 | 702 / 1155 |
| intestine | 79% | 2486.27 | 762 / 966 | 36% | 9.33 | 188 / 527 |
| kidney | 89% | 1380.16 | 79 / 89 | 14% | 2.92 | 128 / 901 |
| adipose | 99% | 7028.29 | 1190 / 1204 | 0% | 0 | 0 / 0 |
| stomach | 52% | 1909.47 | 185 / 359 | 45% | 13.38 | 130 / 286 |
| brain | 2% | 18.14 | 55 / 2642 | 95% | 34.90 | 668 / 705 |
| blood vessel | 92% | 2294.37 | 1224 / 1335 | 0% | 0 | 0 / 0 |
| heart | 81% | 1768.43 | 701 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 68% | 724.43 | 176 / 258 | 13% | 1.61 | 29 / 230 |
| tonsil | 0% | 0 | 0 / 0 | 78% | 24.28 | 35 / 45 |
| eye | 0% | 0 | 0 / 0 | 78% | 12.12 | 62 / 80 |
| muscle | 63% | 819.89 | 509 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 48% | 7.25 | 14 / 29 |
| spleen | 29% | 305.97 | 69 / 241 | 0% | 0 | 0 / 0 |
| liver | 4% | 36.32 | 9 / 226 | 6% | 0.90 | 25 / 406 |
| peripheral blood | 0% | 3.12 | 2 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008589 | Biological process | regulation of smoothened signaling pathway |
| GO_0060628 | Biological process | regulation of ER to Golgi vesicle-mediated transport |
| GO_0048589 | Biological process | developmental growth |
| GO_0042981 | Biological process | regulation of apoptotic process |
| GO_0045930 | Biological process | negative regulation of mitotic cell cycle |
| GO_0045165 | Biological process | cell fate commitment |
| GO_0010955 | Biological process | negative regulation of protein processing |
| GO_0035924 | Biological process | cellular response to vascular endothelial growth factor stimulus |
| GO_0098552 | Cellular component | side of membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0005515 | Molecular function | protein binding |
| GO_0008142 | Molecular function | oxysterol binding |
| Gene name | GAS1 |
| Protein name | Growth arrest-specific protein 1 (GAS-1) |
| Synonyms | |
| Description | FUNCTION: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells. Binds 20(S)-hydroxycholesterol (20(S)-OHC) (By similarity). . |
| Accessions | ENST00000298743.9 P54826 |