Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 14 studies | 37% ± 16% | |
basal cell | 6 studies | 27% ± 12% | |
respiratory goblet cell | 5 studies | 17% ± 2% | |
endothelial cell | 5 studies | 27% ± 12% | |
epithelial cell | 5 studies | 37% ± 18% | |
GABAergic neuron | 5 studies | 34% ± 15% | |
secretory cell | 4 studies | 20% ± 3% | |
glutamatergic neuron | 4 studies | 40% ± 14% | |
squamous epithelial cell | 3 studies | 43% ± 17% | |
ciliated cell | 3 studies | 16% ± 0% | |
club cell | 3 studies | 25% ± 3% | |
ependymal cell | 3 studies | 36% ± 21% | |
goblet cell | 3 studies | 31% ± 20% | |
keratinocyte | 3 studies | 21% ± 3% | |
interneuron | 3 studies | 39% ± 20% | |
neuron | 3 studies | 27% ± 7% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 32% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1987.09 | 1445 / 1445 | 100% | 11.94 | 183 / 183 |
brain | 100% | 1669.12 | 2638 / 2642 | 100% | 10.24 | 704 / 705 |
stomach | 99% | 1003.45 | 357 / 359 | 100% | 5.69 | 285 / 286 |
intestine | 100% | 1433.05 | 966 / 966 | 99% | 5.16 | 522 / 527 |
bladder | 100% | 1127.48 | 21 / 21 | 98% | 5.35 | 493 / 504 |
breast | 99% | 1057.27 | 456 / 459 | 98% | 3.92 | 1098 / 1118 |
prostate | 100% | 1507.71 | 245 / 245 | 97% | 3.09 | 485 / 502 |
lung | 99% | 1190.49 | 573 / 578 | 97% | 5.11 | 1124 / 1155 |
uterus | 100% | 1203.75 | 170 / 170 | 96% | 6.04 | 440 / 459 |
thymus | 99% | 900.09 | 649 / 653 | 93% | 2.11 | 561 / 605 |
skin | 100% | 8775.09 | 1808 / 1809 | 89% | 2.79 | 420 / 472 |
ovary | 100% | 944.34 | 180 / 180 | 82% | 1.71 | 353 / 430 |
pancreas | 84% | 444.47 | 276 / 328 | 97% | 4.22 | 173 / 178 |
adrenal gland | 95% | 579.84 | 244 / 258 | 84% | 1.76 | 193 / 230 |
kidney | 82% | 465.64 | 73 / 89 | 84% | 1.83 | 754 / 901 |
ureter | 0% | 0 | 0 / 0 | 100% | 12.35 | 1 / 1 |
adipose | 99% | 931.52 | 1197 / 1204 | 0% | 0 | 0 / 0 |
spleen | 99% | 668.13 | 238 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 783.06 | 1318 / 1335 | 0% | 0 | 0 / 0 |
liver | 69% | 338.65 | 157 / 226 | 29% | 0.50 | 118 / 406 |
tonsil | 0% | 0 | 0 / 0 | 96% | 6.50 | 43 / 45 |
muscle | 93% | 592.20 | 746 / 803 | 0% | 0 | 0 / 0 |
heart | 91% | 650.64 | 787 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 69% | 1.73 | 20 / 29 |
eye | 0% | 0 | 0 / 0 | 59% | 1.12 | 47 / 80 |
peripheral blood | 22% | 204.69 | 208 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0016567 | Biological process | protein ubiquitination |
GO_0007010 | Biological process | cytoskeleton organization |
GO_0005856 | Cellular component | cytoskeleton |
GO_0005829 | Cellular component | cytosol |
GO_0031463 | Cellular component | Cul3-RING ubiquitin ligase complex |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
GO_0003674 | Molecular function | molecular_function |
Gene name | GAN |
Protein name | Gigaxonin Epididymis secretory sperm binding protein (Giant axonal neuropathy (Gigaxonin)) (Gigaxonin isoform 1) Gigaxonin (Kelch-like protein 16) |
Synonyms | hCG_22116 KLHL16 GAN1 |
Description | FUNCTION: Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival. . |
Accessions | ENST00000648994.2 A0A3B3ITY2 Q9H2C0 ENST00000650388.1 A0A0S2Z4W2 ENST00000648349.2 A0A0S2Z5G5 |