GAD1 | OmnibusX

Name	Number of supported studies	Average coverage
GABAergic neuron	11 studies	55% ± 23%	Explore
oligodendrocyte precursor cell	10 studies	36% ± 16%	Explore
interneuron	7 studies	68% ± 19%	Explore
amacrine cell	6 studies	41% ± 18%	Explore
GABAergic amacrine cell	4 studies	51% ± 15%	Explore
GABAergic interneuron	3 studies	62% ± 13%	Explore

Name	Number of supported studies	Average coverage
brain	7 studies	25% ± 7%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	96%	5898.65	2530 / 2642	98%	25.73	690 / 705
adrenal gland	71%	480.20	182 / 258	67%	6.44	154 / 230
ureter	0%	0	0 / 0	100%	2.12	1 / 1
kidney	62%	456.67	55 / 89	30%	1.30	267 / 901
blood vessel	72%	666.06	963 / 1335	0%	0	0 / 0
uterus	7%	36.52	12 / 170	57%	3.03	261 / 459
tonsil	0%	0	0 / 0	62%	1.76	28 / 45
bladder	10%	32.38	2 / 21	41%	1.58	206 / 504
esophagus	0%	1.03	4 / 1445	46%	1.61	84 / 183
pancreas	0%	0	0 / 328	44%	1.11	78 / 178
lung	0%	0.62	1 / 578	42%	1.64	490 / 1155
intestine	0%	0.39	1 / 966	42%	1.51	223 / 527
stomach	0%	0	0 / 359	34%	1.48	96 / 286
prostate	7%	29.22	16 / 245	26%	0.46	129 / 502
skin	0%	0.58	1 / 1809	21%	0.75	98 / 472
ovary	0%	0	0 / 180	16%	0.51	67 / 430
breast	0%	0.70	1 / 459	14%	1.20	161 / 1118
liver	0%	0	0 / 226	12%	0.30	49 / 406
lymph node	0%	0	0 / 0	10%	0.24	3 / 29
peripheral blood	3%	21.27	30 / 929	0%	0	0 / 0
thymus	0%	6.56	2 / 653	2%	0.07	14 / 605
eye	0%	0	0 / 0	3%	0.26	2 / 80
spleen	0%	1.33	1 / 241	0%	0	0 / 0
adipose	0%	0.69	2 / 1204	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
heart	0%	0	0 / 861	0%	0	0 / 0
muscle	0%	0	0 / 803	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0006540	Biological process	glutamate decarboxylation to succinate
GO_0007268	Biological process	chemical synaptic transmission
GO_0006538	Biological process	glutamate catabolic process
GO_0035176	Biological process	social behavior
GO_0035641	Biological process	locomotory exploration behavior
GO_0009449	Biological process	gamma-aminobutyric acid biosynthetic process
GO_0061202	Cellular component	clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
GO_0005886	Cellular component	plasma membrane
GO_0012506	Cellular component	vesicle membrane
GO_0060077	Cellular component	inhibitory synapse
GO_0043679	Cellular component	axon terminus
GO_0098982	Cellular component	GABA-ergic synapse
GO_0048786	Cellular component	presynaptic active zone
GO_0005938	Cellular component	cell cortex
GO_0005737	Cellular component	cytoplasm
GO_0030170	Molecular function	pyridoxal phosphate binding
GO_0042802	Molecular function	identical protein binding
GO_0005515	Molecular function	protein binding
GO_0004351	Molecular function	glutamate decarboxylase activity

Gene name	GAD1
Protein name	Glutamate decarboxylase 1 isoform 2 Glutamate decarboxylase 1 (EC 4.1.1.15) Glutamate decarboxylase 1 isoform 3 Glutamate decarboxylase 1 Glutamate decarboxylase 1 (EC 4.1.1.15) (67 kDa glutamic acid decarboxylase) (GAD-67) (Glutamate decarboxylase 67 kDa isoform)
Synonyms	GAD GAD67
Description	FUNCTION: Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor. .; FUNCTION: [Isoform 3]: Enzymatically inactive as glutamate decarboxylase. . FUNCTION: Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor. . FUNCTION: Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor. .
Accessions	ENST00000493875.5 [Q99259-4] ENST00000486850.1 C9JT43 ENST00000344257.9 [Q99259-3] ENST00000414527.6 Q8IVA8 A0A0S2Z3U2 Q99259 ENST00000375272.5 [Q99259-3] U3KQR2 C9JLZ7 ENST00000456864.5 A0A0S2Z3V5 C9JN45 ENST00000358196.8 [Q99259-1] ENST00000625689.2 [Q99259-4] A0A0S2Z4D9 ENST00000454603.5 ENST00000455008.5 F8WD43 ENST00000445006.5 C9J6C9

GAD1 report